A Forgotten Encounter: A Case of Amebic Liver Abscess Mimicking Hepatic Malignancy in a Non-endemic Region.

Amebic liver abscess (ALA), caused by , is prevalent in endemic regions such as Central/South America, Southeast Asia/India, and Africa but is considered rare in North America. Symptoms of infection typically emerge eight to 20 weeks after exposure in endemic areas. We present the case of a 58-year-old woman who developed right-sided abdominal pain, weakness, fever, and significant weight loss.

Intracellular calcium dysregulation in autism spectrum disorder: An analysis of converging organelle signaling pathways.

Autism spectrum disorder (ASD) is a group of complex, neurological disorders that affect early cognitive, social, and verbal development. Our understanding of ASD has vastly improved with advances in genomic sequencing technology and genetic models that have identified >800 loci with variants that increase susceptibility to ASD. Although these findings have confirmed its high heritability, the underlying mechanisms by which these genes produce the ASD phenotypes have not been defined.