Pilot study to assess the safety and efficacy of human acellular dermal matrix for Chiari surgery.

Purpose: Although there may be benefits to adult patients who have had Chiari surgery when duroplasty is indicated, there are also more risks involved. The complications derived from a non-hermetic dural closure in the posterior fossa can be significant, mainly cerebrospinal fluid (CSF) leakage, meningitis and pseudomeningocele. We explored the option of utilizing a different duroplasty that we typically utilized in order to reduce these risks.

Periventricular gliomas: Evaluation of the risks associated with ventricular opening in two cohorts-one prospective with TachoSil® for ventricular sealing and the other without it retrospective.

Introduction: Historically, ventricular opening (VO) has been associated with a greater risk of postoperative complications and a risk of leptomeningeal spread (LMS) in periventricular gliomas especially high grade gliomas. There are no specific products on the market for ventricular sealing with registered studies. TachoSil® is widely used for supportive sealing of the dura mater.

Effectiveness and safety of Tachosil® as a ventricular sealant: an observational cohort study.

Purpose: Surgery close to or in contact with the ventricular system is challenging due to the complications. We sought to evaluate the effectiveness and safety of TachoSil® as a ventricular sealant in preventing complications after cranial surgery with an open ventricular system (OVS).

Methods: This is a single-center and prospective cohort study We included patients who underwent elective surgery for supratentorial craniotomy and periventricular pathology between December 2020 and November 2023.

Growth prediction in asymptomatic meningiomas: the utility of the AIMSS score.

Background: Management of asymptomatic meningiomas represents a challenge due to the absence of a solid consensus on which is the best management strategy. There are various known factors predicting meningiomas growth risk. However, the Asian Intracranial Meningioma Scoring System (AIMSS) is the only described score to quantify such risk thus emerging as a potential tool for management decisions.