Relationship between somatic symptoms with menstruation and intention to leave work among university hospital nurses in Japan: a cross-sectional study.

Purpose: This study investigated the association between menstrual symptoms and the intention to leave work among female nurses in Japan.

Methods: This cross-sectional study investigated female nurses (n = 317) at two university hospitals. The items measured were their characteristics (e.

High purity tocotrienols attenuate atherosclerotic lesion formation in apoE-KO mice.

Previous studies have demonstrated that tocotrienol (T3) has antiatherogenic effects. However, the T3 preparations used in those studies contained considerable amounts of tocopherol (Toc), which might affect the biological activity of T3. There is little information on the effect of highly purified T3 on atherosclerosis formation.

Physiological effects and tissue distribution from large doses of tocotrienol in rats.

Supplementation to an AIN93G-based diet of tocotrienol (T3) for 13 weeks administered to Fischer 344/slc rats showed a safety profile with no side effects. Dose-dependent T3 levels were detected in many tissues. Under the present experimental conditions, a continuous intake of the T3 concentrate would be safe in the rats as long as the T3 content was less than 0.