Gene profiling and expression of major allergen Alt a 1 in Alternaria alternata and related members of the Pleosporaceae family.

Background: Members of the Pleosporaceae family are known as important sources of airborne allergens which are responsible for asthma and allergic diseases.

Aims: The purpose of this study was to investigate the gene profiling and expression pattern of Alt a 1 in Alternaria alternata and other members of the Pleosporaceae family including Stemphylium botryosum, Ulocladium chartarum, Curvularia lunata, Cladosporium cladosporioides, and Epicoccum nigrum.

Methods: Alternaria alternata and related genera were cultured on Czapek-Dox broth medium at 25°C for 21 days.

Sensitization and Geographical Distribution of Main Aeroallergens in Iran.

N0 Abstract.

The major Alternaria alternata allergen, Alt a 1: A reliable and specific marker of fungal contamination in citrus fruits.

The ubiquitously present spores of Alternaria alternata can spoil a wide variety of foodstuffs, including a variety of fruits belonging to the Citrus genus. The major allergenic protein of A. alternata, Alt a 1, is a species-specific molecular marker that has been strongly associated with allergenicity and phytopathogenicity of this fungal species.

Learning from the Molecular Profile of Blattella Germanica Allergens Identified from Allergic Patients in Tehran, Iran.

No Abstract.

Emergence of azole-resistant species in AIDS patients with oropharyngeal candidiasis in Iran.

Background And Purpose: Oropharyngeal candidiasis (OPC) and antifungal drug resistance are major health concerns in patients with human immunodeficiency virus (HIV). The increased reports of antifungal resistance and expanding drug therapy options prompted the determination of antifungal susceptibility profile. The present study was performed to determine the antifungal susceptibility of species isolated from AIDS patients with OPC in Iran.

Identification of the main allergen sensitizers in an Iran asthmatic population by molecular diagnosis.

Background: There has been a significant growth in the prevalence of allergy, mainly associated to IgE-mediated disorders such as asthma and rhinitis. The identification of atopy in asthmatic patients through the measurement of specific IgE can help to identify risk factors that cause asthmatic symptoms in patients. The development and use of individualized allergen-based tests by the Component Resolved Diagnosis has been a crucial advance in the accurate diagnosis and control of allergic patients.