Changes in higher-order aberrations after implantation of a foldable iris-claw lens in myopic phakic eyes.

Purpose: To evaluate the change in higher-order aberrations (HOAs) after implantation of a foldable iris-claw phakic intraocular lens (pIOL) in myopic eyes.

Setting: Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany.

Methods: This prospective nonrandomized comparative self-controlled trial included 41 eyes that had implantation of a foldable iris-claw pIOL between July 2003 and November 2004.

The "sandwich technique" for iris-fixated phakic intraocular lens implantation.

Purpose: To describe a new technique of implantation of the Artisan/Verisyse phakic intraocular lens (PIOL).

Methods: After PIOL insertion into the anterior chamber, a bolus of a high viscosity ophthalmic viscosurgical device (OVD) is placed over the optic, separating it widely from the endothelium.

Results: The technique decreases the chance of endothelial damage during enclavation.

Laparoscopic cholecystectomy and open-heart surgery at the same time.

Background: Abdominal procedures in patients with coronary artery disease or severe valvular disease have high risk of mortality and morbidity.

Aims: In order to prevent bile peritonitis after cardiac surgery, to reduce the hospitalization course, and to decrease the mortality and morbidity after the surgery, laparoscopic cholecystectomy and open-heart surgery were performed at the same time.

Methods: Laparoscopic cholecystectomy and open-heart surgery were performed on two patients who had been referred to Cardiothoracic Ward of Modarres Hospital, Tehran, Iran.

Short-term follow-up after implantation of a foldable iris-fixated intraocular lens in phakic eyes.

Objective: To evaluate efficiency, predictability, stability, complications, and patient satisfaction after implantation of a foldable iris-fixated phakic intraocular lens (PIOL) for the correction of myopia.

Design: Prospective, nonrandomized, comparative (self-controlled) trial.

Participants: Forty-one eyes of 22 myopic patients aged 18 to 56 years (mean, 36 years) with average sphere of -8.

Change in pupil size after implantation of an iris-fixated toric phakic intraocular lens.

Purpose: To evaluate the changes in pupil size after implantation of an iris-supported toric phakic intraocular lens (TPIOL) for correction of myopia and hyperopia with astigmatism.

Setting: Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany.

Methods: Twenty-two myopic eyes and 9 hyperopic eyes were included in the study.

Evaluation of cut quality using the Amadeus microkeratome with different settings.

Purpose: To evaluate the quality of keratectomy specimens created with the Amadeus microkeratome (AMO) using scanning electron microscopy (SEM).

Setting: Johannes Gutenberg-University Hospital, Department of Ophthalmology, Mainz, and the Department of Anatomy, Justus Liebig-University, Giessen, Germany.

Methods: Corneal cuts were performed in freshly enucleated pig eyes using the Amadeus microkeratome with 9 combinations of oscillation rate and head-advance speed.

Contrast sensitivity after implantation of toric iris-claw lenses in phakic eyes.

Purpose: To evaluate the change in contrast sensitivity after implantation of the Verisyse toric phakic intraocular lens (IOL) (AMO) for the correction of myopia with astigmatism.

Setting: Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany.

Methods: Eighteen eyes had implantation of an iris-supported toric phakic IOL to correct myopia with astigmatism.

[Microbial keratitis following laser in situ keratomileusis. Prevention, differential diagnosis, and therapy].

Laser in situ keratomileusis (LASIK) is an effective option and currently one of the most commonly applied surgical techniques in the correction of refractive errors such as myopia, hyperopia, and astigmatism. In contrast to photorefractive keratectomy, it maintains the integrity of Bowman's membrane and the epithelium leading to faster visual rehabilitation as well as less pain and discomfort. Nevertheless, following LASIK the stroma is exposed to infectious organisms.

Impact of the line of sight on toric phakic intraocular lenses for hyperopia.

We present a hyperopic patient with a decentered line of sight in whom the residual refractive error after toric phakic intraocular lens (TP IOL) implantation was improved by displacement and individualized treatment. A 35-year-old woman presented with asthenopic complaints 2 months after bilateral TP IOL implantation and IOL rotation 4 weeks later. Examination revealed the line of sight to be nasally and inferiorly decentered in relation to the center of the pupil.

Disease-specific assessment of quality of life after decompression surgery for Graves' ophthalmopathy.

Purpose: Graves' ophthalmopathy (GO) is an organ-specific autoimmune disease. Hydrophily of accumulated acidic mucopolysaccharides into bulbar adipose tissue leads to swelling of the eye muscles. Orbital surgical decompression is performed in severe cases of compressive optic neuropathy and severe corneal exposure or failure of steroid therapy.

Solid-phase microextraction (SPME) of permethrin residues from cucumber using a silica-bonded phase-coated stainless steel fibre.

Solid-phase microextraction (SPME) is a rapid, economic and solvent-free sample preparation method for the isolation of an analyte from its matrix. The technique uses a few centimetres of some adsorptive materials such as activated charcoal, polydimethylsiloxane or octadecyl silane coated onto fused silica optical fibres or, more recently, stainless steel fibres mounted into a microsyringe. The proposed method allows the extraction of permethrin from cucumber matrix into the coating, avoiding sample handling and saving evaporation of solvents and concentration steps.

Localized nodular hypertrophy mimicking rhabdomyoma in the fetal heart: prenatal sonographic and pathology findings.

Multiple intracardiac masses (ICM) are considered to be diagnostic of rhabdomyoma often associated with tuberous sclerosis. We describe a fetus with multiple ICM detected by fetal sonography at 18.7 wk gestation.

Disease-specific assessment of quality of life after decompression surgery for Graves ophthalmopathy.

Purpose: Graves ophthalmopathy (GO) is an organ-specific autoimmune disease. Hydrophily of accumulated acidic mucopolysaccharides into bulbar adipose tissue leads to swelling of the eye muscles. Orbital surgical decompression is performed in severe cases of compressive optic neuropathy and severe corneal exposure or failure of steroid therapy.

[Phakic intraocular lenses. Current status and limitations].

Phakic intraocular lenses (PIOLs), which are located closer to the eye's nodal points than the anterior corneal surface, can provide superior optical quality for higher corrections because of retention of normal prolate corneal asphericity and larger effective optical zones. Improvements in the material and design of phakic intraocular lenses and their insertion devices combined with advances in the understanding of the anatomical and physiological interactions of the PIOLs with intraocular structures, have increased safety and efficacy. Safety of these implants over the long term remains a concern, but in several situations PIOLs are the refractive correction of choice.

Late postoperative opacification of MemoryLens hydrophilic acrylic intraocular lenses: case series and review.

Purpose: To report clinical and spectrographic analyses of 2 explanted hydrophilic acrylic intraocular lenses (IOLs).

Setting: John A. Moran Eye Center, Salt Lake City, Utah, USA, and Johannes Gutenberg-University, Department of Ophthalmology, Mainz, Germany.

[Laser in situ keratomileusis with a flying-spot excimer laser and a carriazo-barraquer microkeratome - outcomes after 6 months].

Purpose: To evaluate safety, efficacy, predictability and refractive stability of LASIK, using a flying-spot excimer laser, 91 eyes were examined during a 6-months follow-up.

Patients And Methods: Consecutively, 91 eyes were enrolled in the study, each eye previously underwent LASIK with the ESIRIS excimer laser (ESIRIS, supplier: eye-tech-solutions Schwind, Kleinostheim, Germany). 91 myopic eyes (mean preoperative refraction: - 5.

Implantation of a custom intraocular lens with a 30-diopter torus for the correction of high astigmatism after penetrating keratoplasty.

We present a 62-year-old woman who had implantation of an intraocular lens (IOL) with a torus of 30.0 diopters (D) in an eye after penetrating keratoplasty. The patient presented with cataract and a best corrected visual acuity of 20/400.

Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues.

The natural triterpene betulinic acid and its analogues (betulinic aldehyde, lupeol, betulin, methyl betulinate and betulinic acid amide) caused concentration-dependent alterations of erythrocyte membrane shape towards stomatocytes or echinocytes according to their hydrogen bonding properties. Thus, the analogues with a functional group having a capacity of donating a hydrogen bond (COOH, CH(2)OH, CONH(2)) caused formation of echinocytes, whereas those lacking this ability (CH(3), CHO, COOCH(3)) induced formation of stomatocytes. Both kinds of erythrocyte alterations were prohibitive with respect to Plasmodium falciparum invasion and growth; all compounds were inhibitory with IC(50) values in the range 7-28 microM, and the growth inhibition correlated well with the extent of membrane curvature changes assessed by transmission electron microscopy.

Material properties of various intraocular lenses in an experimental study.

Introduction: With the recent introduction of small-incision cataract surgery, requirements for intraocular lens (IOL) flexibility, strength and hydrophilicity have rapidly evolved. The IOL surface, however, remains a critical factor influencing uveal biocompatibility.

Purpose: To objectively quantify factors of material properties of various IOLs using contact angle measurements, differential scanning calorimetry, dynamic-mechanical measurements and scanning electron microscopy.

Capsule measuring ring to predict capsular bag diameter and follow its course after foldable intraocular lens implantation.

Purpose: To evaluate the extent of capsular bag shrinkage after cataract surgery with intraocular lens (IOL) implantation and develop a regression formula to predict postoperative capsular bag size.

Setting: Eye Hospital, Johannes Gutenberg-University, Mainz, Germany.

Methods: The axial length (AL), anterior chamber depth, and corneal radius in 58 eyes were measured preoperatively.

Postoperative astigmatism and rotational stability after artisan toric phakic intraocular lens implantation.

Purpose: To evaluate deviations in the axis (intended versus achieved) and postoperative astigmatism after implantation of an Artisan toric phakic intraocular lens (IOL).

Setting: University Eye Hospital, Mainz, Germany.

Methods: This prospective study comprised 29 eyes with high ametropia and astigmatism.

[Cost effectiveness evaluation of cataract patient care in respect of monofocal intraocular lenses from the perspective of German statutory health insurance].

Background: Data on the cost effectiveness of cataract surgery with respect to the German statutory health insurance system are hardly available. Hence the increase in visual acuity as primary efficacy endpoint, order of posterior capsule opacification as primary complication endpoint and direct cost for supplementation with monofocal intraocular lenses have been assessed via meta-analyses to evaluate the procedure's cost effectiveness from the perspective of the German statutory health insurance system.

Material And Methods: Using the medical internet database MEDLINE two meta-analyses on publications between 1995 and 2002 were carried out, one estimating the gained increase in visual acuity, the second to estimate the frequency of posterior capsule opacification 5 years after implantation of a monofocal lens.

[Complications of foldable intraocular lenses requiring explantation. Results of the 2000 and 2001 survey in Germany].

Purpose: A survey was sent to all members of the German Society of Ophthalmic Surgeons to evaluate complications that required explantation of foldable intraocular lenses (IOLs).

Methods: Data on preoperative visual acuity, foldable IOL design and material, and the reason for explantation were obtained and analysed. We received 185 surveys for 2000 and 2001.

Comparison of biometric measurements using partial coherence interferometry and applanation ultrasound.

Purpose: To compare and contrast axial length (AL) measurements assessed by ultrasound biometry and optical biometry.

Setting: Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany.

Methods: Optical biometry and ultrasound biometry were performed in 360 eyes to measure AL.