Survival within 12months after stroke in Madagascar.

The data on the long-term prognosis of stroke are scarce in Madagascar. Our objective was to determine survival within 12months after a stroke event. A longitudinal study was carried out on a hospital cohort of subjects with stroke in Mahajanga in western Madagascar.

Gait and cognitive disorders revealing massive neurocysticercosis: a case report.

Neurocysticercosis is frequent in Madagascar. Its clinical presentations depends on the topography of the lesions. We report a case with gait and cognitive disorders.

Correlation between silent lacunar strokes and retinopathies seen on fundus among patients hospitalized for lacunar strokes: An observational study at the neurology department of Befelatanana University Hospital.

Retinal and cerebral arterioles have similar characteristics. Silent infarcts are associated with a risk of incident lacunar stroke and dementia. The objective of our study was to determine the correlation between silent lacunar strokes and retinopathy in patients hospitalized in our department for lacunar strokes.

Cerebral venous thrombosis associated with infective endocarditis in a young patient.

Cerebral venous thrombosis (CVT) is a rare complication of infective endocarditis. It constitutes a diagnostic and therapeutic emergency. We report a case of cerebral thrombophlebitis due to infective endocarditis in order to discuss the diagnosis and management of this situation.

[Intra-hospital and three-month outcomes of patients with cerebral venous thrombosis in the department of neurology in Befelatanana, Madagascar: a retrospective cohort study].

The prognosis of cerebral venous thrombosis (CVT) is much better than that of cerebral artery (CAI) infarct. The purpose of this study is to describe intra-hospital and three-month outcomes of patients with CVT in the Department of Neurology of Befelatanana as well as the role of anticoagulants in the management of patients with CVT, without and with haemorrhagic suffusion. We conducted a retrospective cohort study of patients with CVT from January 01, 2014 to December 31, 2019 (72 months).

[Frequency and clinico-therapeutic features of patients with status epilecticus hospitalized in the department of neurology of the Bafelatanana hospital, Antananarivo, Madagascar].

Introduction: Status Epilepticus (SE) is a diagnostic and therapeutic emergency. The purpose of this study was to establish the frequency, the clinical and therapeutic features of patients with SE at the Department of Neurology of Befelatanana.

Methods: we conducted a retrospective, descriptive study from January to June 2015.

[Clinical course of myasthenia gravis at the department of neurology in Antananarivo Madagascar].

Introduction: myasthenia gravis (MG) is a rare disease affecting the neuromuscular junction. It can lead to a life-threatening condition, especially when it is associated with respiratory failure. Full remission is possible with treatment.

[Epilepsy and reproductive health: challenges and prospects].

Epilepsy complicates a woman's reproductive life. The physiological modification of the woman and the effects of antiepileptic drugs are generally the cause. Several complications may be added during treatment that requires careful monitoring.

[Frequency and clinical profile of Parkinson's disease and other Parkinsonian syndromes seen in the Department of Neurology at the Befelatanana Hospital Antananarivo].

Introduction: Currently we have no precise data on the parkinsonian syndromes in Madagascar. This study aims to collect data on these diseases and to describe the frequency and the clinical profile of parkinsonian syndromes in our Department of Neurology.

Methods: We conducted a retrospective and descriptive study in the Department of Neurology, in Befelatanana from January 2014 to June 2018.

Motor deficit outcome in patients with stroke in the neurology unit of the Befelatanana University Hospital in Antananarivo.

A stroke is the sudden onset of focal neurological deficits presumed to have mecanism vascular and is the leading cause of acquired motor disability in adults. To improve stroke management, we examined the motor disability of patients presenting with stroke, their course, and its determinant factors. This retrospective descriptive study reviewed case records from the neurology unit of the Befelatanana University Hospital from january to december 2015.

[Frequency and characteristics of strokes involving the perforating arteries in the Department of Neurology at the Befelatanana General Hospital, Antananarivo].

Introduction: Strokes of the perforating arteries are mainly arteriolopathies. They result in dementia and stroke recurrence. This study aimed to evaluate the frequency and characteristics of these strokes to better prevent these complications.

Migraine among university students in Cotonou (Benin).

Background: Few data are available on migraine among students in Africa. The aim of this study was to estimate the prevalence of migraine and describe its clinical features and associated conditions among students of the Faculty of Health Sciences of Abomey-Calavi University, in Cotonou, Benin.

Methods: A cross-sectional study was prospectively conducted during the academic year 2002-2003 and included 336 students selected using systematic random sampling.

Autosomal dominant migraine with MRI white-matter abnormalities mapping to the CADASIL locus.

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an autosomal dominant cerebral arteriopathy mapped to chromosome 19 and characterized mainly by recurrent subcortical ischemic strokes and extensive white-matter signal abnormalities (WMAs) on magnetic resonance imaging. Other clinical features include migraine attacks and progressive subcortical dementia. Herein, we describe several members of the same family who suffered migraine attacks, mostly with aura, associated with WMAs, segregating with an autosomal dominant pattern of inheritance.

Case-control study of migraine and risk of ischaemic stroke in young women.

Objective: To determine whether migraine is a risk factor for ischaemic stroke in young women.

Design: A case-control study.

Setting: Five hospitals in Paris and suburbs.

5HT2 receptors in cerebral cortex of migraineurs studied using PET and 18F-fluorosetoperone.

Since the brain 5HT2 receptors might be implicated in migraine pathogenesis, we have used positron emission tomography and 18F-fluorosetoperone, a 5HT2 specific radioligand, to investigate in vivo the cortical 5HT2 receptors in migraine subjects. Nine migraineurs who had either migraine with and without aura (n = 5) or only migraine without aura (n = 4) were studied between attacks. Twelve unmedicated healthy subjects of similar mean age were used as controls.

Long-term compliance to continuous positive airway pressure therapy (nCPAP) set up during a split-night polysomnography.

We studied prospectively the acute and long-term compliance with nasal continuous positive airway pressure (nCPAP) therapy set up during a split-night polysomnography in 31 patients suffering from severe obstructive sleep apnea syndrome (OSAS). The mean apnea-hypopnea index (AHI) was 66 +/- 23/hour. An effective nCPAP (AHI < 10/hour in all sleep stages in the dorsal decubitus) was titrated in 27/31 patients.

[Respiratory effects of midazolam in patients with obstructive sleep apnea syndromes].

The administration of benzodiazepines at sleeping doses can be followed by an increased rate of upper airways obstruction episodes, especially in patients with an obstructive sleep apnea syndrome (OSAS). However, the effects of benzodiazepines at premedication doses have not yet been assessed. Therefore, fourteen patients were studied after administration of midazolam 0.

Migraine and risk of ischaemic stroke: a case-control study.

Objectives: To determine whether migraine is a risk factor for ischaemic stroke.

Design: A case-control study.

Setting: Two hospitals in Paris.

Headache following carotid endarterectomy: a prospective study.

The occurrence of headache in the 28 days following surgery was studied in 50 consecutive patients (14F and 36M, mean aged 70 years) who underwent carotid endarterectomy for atheromatous carotid stenosis. Thirty-one patients (62%) reported headache. Headache occurred in the first five days after surgery in 87% of cases.

Ipsilateral cluster headache and chronic paroxysmal hemicrania: two case reports.

We report two patients with ipsilateral attacks of cluster headache and chronic paroxysmal hemicrania. The first patient, a 33-year-old man, started having attacks of chronic cluster headache at the age of 27. At 33, they were replaced by typical attacks of ipsilateral chronic paroxysmal hemicrania which showed a dramatic improvement with indomethacin 150 mg daily.

[What is new in the treatment of migraine?].

No miracle treatment has occurred which would cure the migraineur, but treatments able to improve him are more numerous and better defined. Conditions are now achieved for significant progress in the field of migraine treatment: better knowledge of the pathophysiology progress in the field of migraine treatment: better knowledge of the pathophysiology of the attack, definition of diagnostic criteria unanimously accepted and of rigorous and specific methodologic rules for therapeutic trials in migraine, discovery of new drugs such as more and more specific agonists or antagonists of serotonin-receptors subtypes.