Publications by authors named "Tehilla Apfel"
Nonalcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver in the absence of secondary causes. NAFLD is a multifactorial disease that results from the interaction of genetic predisposition and metabolic, inflammatory and environmental factors. Among these factors, dysregulation of gut microbiome has been linked to the development of fatty liver disease.
View Article and Find Full Text PDFRisk of progression of Barrett's esophagus in patients with cirrhosis.
World J Gastroenterol
May 2017
Aim: To study Barrett's esophagus (BE) in cirrhosis and assess progression to esophageal adenocarcinoma (EAC) compared to non-cirrhotic BE controls.
Methods: Cirrhotic patients who were found to have endoscopic evidence of BE confirmed by the presence of intestinal metaplasia on histology from 1/1/2000 to 12/1/2015 at Cleveland Clinic were included. Cirrhotic patients were matched 1:4 to BE controls without cirrhosis.
Article Synopsis
- A study evaluated the safety and effectiveness of sofosbuvir (SOF) and simeprevir (SIM) without ribavirin in treating liver transplant recipients with recurrent hepatitis C genotype 1 (HCV GT1).
- Among 81 patients considered, 67 received the treatment, with high success rates: 90% achieved end-of-treatment virologic response and 88% sustained virologic response (SVR).
- The treatment was well tolerated, requiring minimal adjustments to immunosuppressive medication, demonstrating promising results for this patient population.
Introduction: The intrauterine device (IUD) is a popular family planning method worldwide. Some of the complications associated with insertion of an IUD are well described in the literature. The frequency of IUD perforation is estimated to be between 0.
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