Western-Type CagA are the Most Frequent Type in Mongolian Patients.

infection possessing East-Asian-type CagA is associated with carcinogenesis. Mongolia has the highest mortality rate from gastric cancer. Therefore, we evaluated the CagA status in the Mongolian population.

Initial Trials With Susceptibility-Based and Empiric Anti- Therapies in Mongolia.

Mongolia has a high prevalence of infection and gastric cancer. We conducted a prospective, randomized, single-blind study to evaluate the efficacy of common regimens in Mongolia and to obtain specimens for susceptibility testing. Empiric treatments: 270 patients with confirmed infection were randomized to receive 10 days clarithromycin-triple therapy (Clari-TT) ( = 90), modified bismuth quadruple therapy (M-BQT) ( = 90), or sequential therapy (ST) ( = 90).

Evaluation of serum markers for gastric cancer and its precursor diseases among high incidence and mortality rate of gastric cancer area.

Background: Mongolia has the highest mortality rate of gastric cancer. The early detection of cancer and down-staging screening for high risk patients are essential. Therefore, we aimed to validate serum markers for stratifying patients for further management.

New observations regarding Helicobacter pylori and gastric cancer in Mongolia.

Background: The incidence and mortality of gastric cancer in Mongolia is among the highest in the world.

Methods: This was a case-control study in which upper gastrointestinal endoscopy, gastric histology, Helicobacter pylori testing, and risk factor questionnaires were obtained. Histologic subtypes were determined by Lauren's classification.

Gastric mucosa in Mongolian and Japanese patients with gastric cancer and Helicobacter pylori infection.

Aim: To investigate the characteristics of gastric cancer and gastric mucosa in a Mongolian population by comparison with a Japanese population.

Methods: A total of 484 Mongolian patients with gastric cancer were enrolled to study gastric cancer characteristics in Mongolians. In addition, a total of 208 Mongolian and 3205 Japanese consecutive outpatients who underwent endoscopy, had abdominal complaints, no history of gastric operation or Helicobacter pylori eradication treatment, and no use of gastric secretion inhibitors such as histamine H2-receptor antagonists or proton pump inhibitors were enrolled.