Publications by authors named "Teemu Zetterman"

Article Synopsis
  • The study investigates how different pain syndromes influence levels of pain catastrophizing in patients.
  • A total of 727 chronic pain patients were categorized into groups based on their pain syndrome: breast cancer survivors, fibromyalgia, complex regional pain syndrome, and HIV.
  • Results revealed three distinct clusters of pain catastrophizing: low (mostly breast cancer patients), moderate (predominantly fibromyalgia patients), and high (mainly HIV and CRPS patients), with helplessness being a significant factor in the high catastrophizing group.
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Fibromyalgia patients vary in clinical phenotype and treatment can be challenging. The pathophysiology of fibromyalgia is incompletely understood but appears to involve metabolic changes at rest or in response to stress. We enrolled 54 fibromyalgia patients and 31 healthy controls to this prospective study.

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Background: Patients with fibromyalgia (FM) exhibit low peak oxygen uptake ([Formula: see text]O). We aimed to detect the contribution of cardiac output to ([Formula: see text]) and arteriovenous oxygen difference [Formula: see text] to [Formula: see text] from rest to peak exercise in patients with FM.

Methods: Thirty-five women with FM, aged 23 to 65 years, and 23 healthy controls performed a step incremental cycle ergometer test until volitional fatigue.

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Article Synopsis
  • - Fibromyalgia (FM) patients exhibit differences in heart rate variability (HRV) compared to healthy controls, indicating a connection between dysautonomia and FM symptoms, particularly during cognitive stress tests.
  • - The study found that FM patients had higher baseline heart rates and lower RR intervals than controls, along with a reduced response to mental stress, showing less increase in heart rate and a smaller decrease in RR.
  • - Clustering analysis of FM patients revealed three distinct groups based on HRV characteristics and mood, highlighting varying levels of anxiety and depression alongside differing HRV reactivity.
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Article Synopsis
  • Fibromyalgia (FM) is a chronic pain condition that may have links to neuroinflammation, and the study explores how systemic inflammation, as indicated by high-sensitivity CRP (hsCRP) levels, correlates with symptoms in FM patients.
  • The study included 40 FM patients and 30 healthy controls, measuring hsCRP levels and using the Fibromyalgia Impact Questionnaire (FIQ) to assess the severity of symptoms.
  • Results showed that FM patients generally had higher hsCRP levels, particularly those who were overweight and inactive, and correlated elevated hsCRP with worse symptoms and reduced employment ability, suggesting potential for hsCRP to identify patients needing more support.
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Objectives: Fibromyalgia (FM) patients have an increased risk for glucose metabolism disturbances, and impaired glucose tolerance may be associated with symptom severity. Elevated levels of plasma lactate have been detected in FM patients. Both pyruvate and lactate are produced in glucose metabolism and reflect oxidative metabolism.

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Article Synopsis
  • The study compared how female fibromyalgia (FM) patients respond to cognitive stress versus healthy controls, measuring muscle activity, pain, and stress levels during relaxation and stress phases.
  • Results showed FM patients had significantly higher muscle activity (%EMG), pain intensity, and perceived stress, while having lower muscle rest time compared to controls.
  • The findings indicate that FM patients experience increased pain with repeated stress, suggesting that managing stress and anxiety could help alleviate FM symptoms.
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