Publications by authors named "Teck Lai"

Bats (Order: Chiroptera) is a recognised group of bioindicators due to their sensitivity towards alterations in their immediate surroundings. With the threats of climate change becoming more severe on a daily basis, it is reasonable to collect data on how bat diversity is influenced by elevation. This will be useful to predict and monitor possible upslope shifting of bat species due to increase in surrounding temperature or anthropogenic pressure.

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We have investigated seven voltage-gated sodium channel genes for association with idiopathic generalized epilepsy (IGE). Probands and control DNA were grouped into pools and used to screen 85 single-nucleotide polymorphisms (SNPs), mostly HapMap SNPs tagging the common variation in these genes. Twelve SNPs exhibiting an allele frequency difference between pools were genotyped individually in our sample of 232 probands, 313 controls, and 95 parent-proband trios.

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We have investigated the reported association (p = 0.019) between the A118G single nucleotide polymorphism (SNP) of the opioid receptor micro subunit gene (OPRM1) and idiopathic absence epilepsy (IAE). Five SNPs, including A118G, were investigated by association studies in a sample of 240 probands with idiopathic generalized epilepsy (IGE), including 110 with IAE, and 257 controls.

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