Publications by authors named "Tech Gonzalo Pizarro"
Impact of left ventricular hypertrophy on troponin release during acute myocardial infarction: new insights from a comprehensive translational study.
Rodrigo Fernández-Jiménez Jacobo Silva Sara Martínez-Martínez M Dolores López-Maderuelo Mario Nuno-Ayala Tech Gonzalo Pizarro
J Am Heart Assoc
January 2015
Article Synopsis
- The study explored how left ventricular hypertrophy (LVH) affects the release of cardiac biomarkers during myocardial infarction (MI) in both patients and pigs.
- Results showed that LVH led to significantly higher levels of cardiac troponin I (cTnI) post-MI, but did not influence total creatine kinase (CK) levels or the estimation of infarct size (IS) using CK.
- The findings indicate that cTnI may overestimate IS in patients with LVH and is not reliable for predicting post-infarction left ventricular dysfunction, suggesting the need to consider LV mass when evaluating IS and cardiac health.