Decreased Hemolysis and Improved Hemodynamic Performance of Synchronized Bileaflet Mechanical Valve.

Purpose: This study compared the performance of a newly patented synchronized valve (SV) with that of a commercially available (CAV) bileaflet mechanical heart valve.

Description: A high-speed camera was used to record the leaflet kinematics of the SV vs the CAV along the flow channel. Transvalvular energy loss, effective orifice area, and hemolysis ratios were obtained using a mock circulatory system at two fixed pulse rates and at various cardiac outputs with a fixed aortic pressure.

Design of a recursively-structured valveless device for microfluidic manipulation.

A recursively-structured apparatus based on a pneumatic pumping structure has been investigated numerically and experimentally in the present study. For the T-connected channels, this apparatus demonstrated the ability to manipulate the liquid drop from a first channel to a second channel, while simultaneously preventing flow into the third channel. The microTAS research aimed at biochemical analysis miniaturization and integration has recently made explosive progress.