Publications by authors named "Te Sun"
Antibody-drug conjugates (ADCs) are anticancer drugs that combine cytotoxic small-molecule drugs (payloads) with monoclonal antibodies through a chemical linker and that transfer toxic payloads to tumor cells expressing target antigens. All ADCs are based on human IgG. In 2009, the Food and Drug Administration (FDA) approved gemtuzumab ozogamicin as the initial first-generation ADC.
View Article and Find Full Text PDFArtificial Intelligence in microbiomes analysis: A review of applications in dermatology.
Front Microbiol
February 2023
Article Synopsis
- Microorganisms play a significant role in skin diseases, with their imbalances or external infections contributing to various conditions, and understanding their composition can improve diagnosis and prognosis.
- Recent advancements in large-scale sequencing and AI, particularly machine learning, can help analyze extensive data on microorganisms and their link to skin diseases.
- This review highlights the innovative applications of AI, including recognizing fungi with convolutional neural networks and combining microbial genome sequencing with machine learning for better diagnosis related to skin health.
A comparison was made between two K vitamin analogs. Growth in vitro of Hep G2 hepatoma cells was inhibited both by Compound 5 (Cpd 5), a recently synthesized thioalkyl analog of vitamin K or 2-(2-mercaptoethanol)-3-methyl-1, 4-naphthoquinone, as well as by synthetic vitamin K3 (menadione). Using synchronized Hep G2 hepatoma cells, the actions of both Cpd 5 and vitamin K3 on cell cycle regulating proteins were examined.
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