Major depressive disorder (MDD), and particularly treatment-resistant depression (TRD), lead to high levels of health-care use and disease burden. The aim of this study was to evaluate and compare the health-care resource utilisation and associated costs in these patient groups. It was a population-wide, retrospective analysis of NHS health-care electronic records in northwest London using the Discover-NOW platform, one of the largest interlinked datasets in Europe hosted by Imperial College Health Partners, which contains coded emergency and routine, primary and secondary, physical and mental health data, covering a population of more than 2.
View Article and Find Full Text PDFBackground: Despite the availability of effective therapies, many patients with major depressive disorder (MDD) develop treatment-resistant depression (TRD).
Aims: To evaluate and compare prescribing patterns, contact with specialist services and treatment outcomes in patients with MDD and TRD.
Method: This was a retrospective analysis of linked primary and secondary care National Health Service data in the north-west London Discover-NOW data-set.