Rational computational design and development of an immunogenic multiepitope vaccine incorporating transmembrane proteins of Staphylococcus lugdunensis.

Staphylococcus lugdunensis has emerged as a significant human pathogen, responsible for a range of infections from skin and soft tissue infections to endocarditis and bacteremia. Notably, abscess formation is a common manifestation, reflecting its potential shift from a benign skin commensal to a serious pathogen, akin to infective endocarditis. With the rising prevalence of antibiotic resistance, there is a pressing need for novel therapeutic strategies.

Comparative analysis among the degradation potential of enzymes obtained from against the toxicity of sulfur dyes through molecular docking.

The common bacterium has demonstrated potential in the field of biodegradation. is naturally capable of biodegradation because it carries a variety of enzymes that are essential for the breakdown of different substances. The degradation process is effectively catalyzed by these enzymes.

Impact of COVID-19 pandemic on postgraduate training in Paediatrics.

Objective: To assess the impact of the coronavirus disease-2019 pandemic on paediatric postgraduate training as perceived by the trainees.

Methods: The cross-sectional exploratory study was conducted at the Department of Paediatrics, King Edward Medical University, Lahore, Pakistan, from May to June 2020, and comprised paediatric postgraduate trainees associated with various hospitals across the country who were approached online with a pre-designed 24-item questionnaire during the peak months of the pandemic. Data was analysed using SPSS 25.