Comparative analysis of IgG and IgG subclasses against Plasmodium falciparum MSP-1 in children from five contrasting bioecological zones of Cameroon.

Background: Studies reporting the natural immune responses against malaria in children from different geographical settings in endemic areas are not readily available. This study was aimed at comparing the immune responses against Plasmodium falciparum MSP-1 antigen in children from five contrasting bioecological zones in Cameroon.

Methods: In a cross-sectional survey, children between 2 and 15 years, were enrolled from five ecological strata including the south Cameroonian equatorial forest, sudano-sahelian, high inland plateau, high western plateau, and the coastal strata.

Epidemiological and clinical profile of paediatric malaria: a cross sectional study performed on febrile children in five epidemiological strata of malaria in Cameroon.

Background: In the wake of a decline in global malaria, it is imperative to describe the epidemiology of malaria in a country to inform control policies. The purpose of this study was to describe the epidemiological and clinical profile of paediatric malaria in five epidemiological strata of malaria in Cameroon including: the Sudano-sahelian (SS) strata, the High inland plateau (HIP) strata, the South Cameroonian Equatorial forest (SCEF) strata, the High western plateau (HWP) strata, and the Coastal (C) strata.

Methods: This study involved 1609 febrile children (≤15 years) recruited using reference hospitals in the five epidemiological strata.

Identification of the species in clinical samples from children residing in five epidemiological strata of malaria in Cameroon.

Background: Malaria in Cameroon was previously known to be caused solely by but today, evidence points to other species including , and . The purpose of this study was to identify the species in clinical samples from children residing in five epidemiological strata of malaria in Cameroon, so as to advise control policies.

Methods: One thousand six hundred nine febrile children (≤15 years) were recruited from five epidemiological strata of malaria including the Sudano-sahelian (SS) strata, the High inland plateau (HIP) strata, the South Cameroonian Equatorial forest (SCEF) strata, the High western plateau (HWP) strata and the Coastal (C) strata.

Anaemia and its association with month and blood phenotype in blood donors in Fako division, Cameroon.

Background: Anaemia is one of the main factors in the deferral (disqualification) of blood donors following haematological screening. There is paucity of data on the prevalence of anaemia in blood donors in Sub-Saharan Africa. This study was undertaken to determine the prevalence of anaemia and its association with month and blood phenotype in blood donors in Fako division of Cameroon.

Coinfection with malaria and intestinal parasites, and its association with anaemia in children in Cameroon.

Background: The purpose of this study was to determine the prevalence of coinfection with malaria and intestinal parasites, as well as to determine its association with anaemia in children aged 10 years and below in Muyuka, Cameroon.

Materials And Methods: This was a cross-sectional study. Participants were febrile children who were admitted to the Muyuka district hospital between April and October 2012.

A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis.

Background: New drugs effective against adult filariae (macrofilaricides) would accelerate the elimination of lymphatic filariasis and onchocerciasis. Anti-Onchocerca drug development is hampered by the lack of a facile model. We postulated that SCID mice could be developed as a fmacrofilaricide screening model.