Iron Oxide Nanoparticles for Biomedical Applications: A Perspective on Synthesis, Drugs, Antimicrobial Activity, and Toxicity.

Medical applications and biotechnological advances, including magnetic resonance imaging, cell separation and detection, tissue repair, magnetic hyperthermia and drug delivery, have strongly benefited from employing iron oxide nanoparticles (IONPs) due to their remarkable properties, such as superparamagnetism, size and possibility of receiving a biocompatible coating. Ongoing research efforts focus on reducing drug concentration, toxicity, and other side effects, while increasing efficacy of IONPs-based treatments. This review highlights the methods of synthesis and presents the most recent reports in the literature regarding advances in drug delivery using IONPs-based systems, as well as their antimicrobial activity against different microorganisms.

Stress distribution on short implants with different designs: a photoelastic analysis.

Short dental implants have been used as an attempt to avoid bone grafts surgery, however there are few literature reports that evaluate changes to their design. Therefore, the aim of this study was to assess the effect of different short implant design on stress distribution through photoelastic analysis. Six external hexagon (5 × 5 mm) short dental implants with different design were used.