Publications by authors named "Taym Darwish"
Prevalence of Keratoconus and Keratoconus Suspect among Patients Seeking Refractive Surgery in Syria.
Middle East Afr J Ophthalmol
January 2024
Purpose: The purpose of this study was to determine the prevalence of keratoconus (KC) and keratoconus suspect (KCS) among patients seeking refractive surgery in Syria.
Methods: This is a retrospective multicenter screening study. The study was conducted in Damascus University, Tishreen University, and Tartous Specialist Eye Center (a private center).
Article Synopsis
- The study aimed to assess how accurately corneal and epithelial thickness measurements from spectral-domain optical coherence tomography (SD-OCT) can identify keratoconus (KC) and suspect keratoconus (SKC).
- Researchers analyzed data from 144 eyes categorized into normal, SKC, and KC groups, measuring various thickness parameters and using ROC curve analysis to evaluate diagnostic effectiveness.
- The findings indicated that some epithelial thickness parameters were highly predictive for identifying KC, but both thickness measurements were less effective in differentiating SKC from normal eyes.
Purpose: To compare the root mean square (RMS) of anterior corneal higher-order aberrations (HOAs) in ametropic and emmetropic eyes.
Methods: This retrospective observational study was conducted at the Department of Ophthalmology, Tishreen University Hospital, Latakia, Syria. Study eyes were divided into four groups based on refractive error: mild-to-moderate myopia, hypermetropia, myopic astigmatism, and emmetropic eyes as controls.
Aim: To investigate the application of anterior and posterior corneal higher-order aberrations (HOAs) in detecting keratoconus (KC) and suspect keratoconus (SKC).
Method: A retrospective, case-control study evaluating non-ectatic (normal) eyes, SKC eyes, and KC eyes. The Sirius Scheimpfug (CSO, Italy) analyses was used to measure HOAs of the anterior and posterior corneal surfaces.
Aim: To determine the prevalence and associations of keratoconus (KC) in a university student population in Syria.
Methods: A prospective multicentre cross-sectional cohort study was conducted at two universities in Syria. Student volunteers were recruited from Tishreen University (Latakia governorate) and Damascus University (Damascus governorate).
Aim: To evaluate changes in corneal higher-order aberrations (HOAs) following epithelium-off accelerated corneal cross-linking (A-CXL) and to explore the impact on visual acuity.
Methods: In this retrospective case series, 32 eyes of 24 patients with keratoconus (KC) underwent A-CXL. Treatment was delivered at 10 mW/cm for 9 min with a total dose of 5.
Aim: To assess the efficacy and safety of accelerated corneal cross-linking in the treatment of pediatric keratoconus.
Method: In this retrospective case series, 29 eyes of 20 pediatric patients with keratoconus underwent accelerated corneal cross-linking. Treatment was delivered at 10 mW/cm for 9 minutes with a total dose of 5.
Aim: To estimate the sensitivity and specificity of topographic and tomographic corneal parameters as determined by Sirius (CSO, Florence, Italy) in discriminating keratoconus (KC) and suspect keratoconus from normal cornea.
Method: In this retrospective case-series study, keratoconus screening indices were measured using Sirius tomographer. Receiver operating characteristics (ROC) curves were used to determine the test's overall predictive accuracy (area under the curve) and to identify optimal cut-off points to maximize sensitivity and specificity in differentiating keratoconus and suspect keratoconus from normal corneas.
Aim: To evaluate the long-term outcomes of corneal cross-linking (CXL) in patients with progressive keratoconus.
Method: In this retrospective non-comparative study, forty-five eyes of 31 patients with progressive keratoconus were treated with 30 min "epi-off" corneal cross-linking. The visual, refractive, topographic and tomographic outcomes were evaluated preoperatively and at least 10 years after cross-linking.
Purpose: To compare the outcomes of accelerated versus standard corneal cross-linking for the treatment of progressive keratoconus.
Methods: In this retrospective comparative study, 63 eyes of 40 patients with progressive keratoconus were divided into two groups; 27 eyes in group one were treated with an accelerated protocol (10 mW/cm , 9 min) and 36 eyes in group two were treated with the standard method (3 mW/cm , 30 min). Visual acuity, refraction, corneal topography, corneal tomography, and anterior and posterior corneal higher-order aberrations (HOAs) were assessed preoperatively and 18-30 months postoperatively.
Subbasal nerve regeneration after LASEK measured by confocal microscopy.
J Refract Surg
September 2007
Purpose: To determine the relationship between the degree of subbasal nerve regeneration and corneal sensation and tear film functions after LASEK using corneal confocal microscopy.
Methods: This prospective, observational, and longitudinal study included 35 LASEK patients who underwent tear breakup time assessment, phenol red thread test, corneal esthesiometry, and confocal microscopy preoperatively and 1, 3, and 6 months postoperatively. Subbasal nerve images were analyzed to assess nerve regeneration.
Purpose: To evaluate subbasal nerve regeneration, corneal sensitivity, and tear film function after penetrating keratoplasty.
Methods: Twenty keratoplasty patients were assessed before and 1, 3, 6, and 12 months after penetrating keratoplasty by using noncontact corneal esthesiometry, tear breakup time measurement, the phenol red thread test, and confocal microscopy. Ten healthy control subjects were also assessed by using these techniques on 1 occasion.
Purpose: To evaluate recovery of the corneal subbasal nerve plexus and corneal sensitivity after myopic laser in situ keratomileusis (LASIK) and laser-assisted subepithelial keratectomy (LASEK).
Setting: Manchester Centre for Vision, Royal Eye Hospital, Manchester, United Kingdom.
Methods: Thirty LASEK patients and 20 LASIK patients had slit-scanning confocal microscopy and noncontact corneal esthesiometry preoperatively and 1, 3, and 6 months after surgery.