Publications by authors named "Taylor S Priver"
Key Points: A K-alkali–enriched diet blunted post-uninephrectomy hypertension and facilitated acid clearance by suppressing Na reabsorption. Uninephrectomy-associated proteinuria could be attributed to elevated single-nephron GFR and downregulation of megalin, which reduced fractional protein endocytosis.
Background: Losing or donating a kidney is associated with risks of developing hypertension and albuminuria.
Article Synopsis
- The study looked at how the kidneys and muscles work together to keep potassium levels in the body steady, especially when mice were fed a diet low in potassium.
- When the mice ate no potassium (0K diet), their blood potassium dropped a lot, and muscles lost potassium while gaining sodium.
- The research found that these changes in potassium and sodium were matched by special adjustments in muscle and kidney transporters, which helped the mice manage their potassium levels despite the low intake.