Publications by authors named "Taylor M Rali"
Background: Vancomycin, an antibiotic with activity against methicillin-resistant Staphylococcus aureus (MRSA), is frequently included in empiric treatment for community-acquired pneumonia (CAP) despite the fact that MRSA is rarely implicated in CAP. Conducting polymerase chain reaction (PCR) testing on nasal swabs to identify the presence of MRSA colonization has been proposed as an antimicrobial stewardship intervention to reduce the use of vancomycin. Observational studies have shown reductions in vancomycin use after implementation of MRSA colonization testing, and this approach has been adopted by CAP guidelines.
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- Vancomycin is a strong antibiotic often used for treating pneumonia, but it's rarely needed for a certain type of bacteria called MRSA.
- Doctors want to see if testing patients for MRSA with a simple nose swab can help reduce unnecessary use of vancomycin.
- The STOP-Vanc study will compare two groups of patients: one will get MRSA testing plus regular treatment, and the other will just get regular treatment to see if this helps people stay off vancomycin safely.