Publications by authors named "Taylor Hu"
Article Synopsis
- * Current TCRs targeting G12-mutant KRAS are limited, but researchers found that tumor cells might evade immune attack by presenting a modified, methylated version of the KRAS epitope instead of the unaltered one.
- * A new approach was used to create TCRs that can recognize this methylated peptide, and a gene screen identified a protein called SPT6 that plays a role in the methylation process, indicating a potential strategy to enhance TCR-T cell therapies by targeting these modifications
