Publications by authors named "Taylor A Brown"

Article Synopsis
  • The study examines the outcomes for Medicaid beneficiaries with diabetic foot ulcers (DFUs) who switched to commercial insurance from 2010 to 2019.
  • A total of 8856 patients were included, and the data analysis involved methods like propensity matching to compare outcomes between those with commercial insurance and those who remained on Medicaid.
  • Results showed that transitioning to commercial insurance correlated with a 27% lower risk of major amputation, highlighting potential benefits of insurance type for patients with DFUs.
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Article Synopsis
  • Prurigo nodularis (PN) is a skin condition characterized by itchy lesions that can severely affect a person's quality of life.
  • Its symptoms can resemble those of other skin disorders, making diagnosis challenging and leading to potential misidentification.
  • The treatment landscape for moderate to severe PN has improved with the FDA-approved medication dupilumab, and the review discusses PN's underlying mechanisms, tissue characteristics, and treatment options.
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Pandemic-related distancing regulations gave medical educators at our college an opportunity to reimagine and expand our evidenced-based medicine curriculum to an asynchronous, virtual format. We share the experience of course directors, faculty, and students with our new surgical journal club format. Our goal was to support learners' critical appraisal skills of the surgical literature through active learning modalities such as visual abstract generation and audio-synopsis creation.

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Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine tumor associated with high mortality if metastases are identified. Currently, there is no standardized nor curative treatment for neurometastatic MCC. In this study, we have reviewed the more recent cases and the use of immunotherapy in a population.

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The belief that chromatographic separation of complex environmental mixtures or natural organic matter (NOM) produces featureless humps from which little, if anything, can be learned is still pervasive. Meanwhile improvements in chromatography and the use of information-rich detection methods have led to meaningful fractionation and revealed consistent data. Here, we build on this work and developed a robust, facile two-dimensional separation with high orthogonality between dimensions.

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Article Synopsis
  • As levels of natural organic matter (NOM) increase in surface water, it becomes crucial to minimize harmful disinfection by-products (DBPs) generated during chlorination.
  • Chromatographic prefractionation helps simplify the complex composition of NOM, making it easier to analyze how chlorination alters it.
  • The study found that highly oxidized NOM led to more diverse DBPs and significant changes that complicate detection, while less-oxidized materials formed fewer DBPs and maintained a more stable composition.
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