Publications by authors named "Tayfun Sahin"

Article Synopsis
  • The Myval is a transcatheter heart valve developed by Meril Life Sciences that features an operator-friendly design for easier delivery and precise deployment.
  • It has shown effectiveness and safety in clinical studies, making it suitable for various complex heart valve procedures, including aortic valve implantation and pulmonary valve replacement.
  • The advancement of Myval signifies a step forward in cardiology, with a need for further long-term studies to confirm its benefits in improving patient outcomes and quality of life.*
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: Sjögren Syndrome (SS) is a chronic, systemic, and progressive autoimmune disease in which inflammatory processes play a role. Dry eyes or mouth are present in approximately 95-98% of patients with pSS. This study aimed to evaluate the relationship between SII level and disease activity as well as dry eye involvement in patients with pSS.

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Article Synopsis
  • Dual antiplatelet therapy (DAPT) is crucial for managing patients with coronary artery disease during procedures like percutaneous coronary intervention (PCI), but can pose risks if surgery is needed urgently.
  • Cangrelor, an intravenous medication, allows rapid and potent platelet inhibition, which can be quickly reversed, making it a potential solution for patients needing to temporarily stop DAPT.
  • In a case of a patient with recent PCI who developed an esophageal perforation, prolonged cangrelor use effectively helped manage the situation without causing any thrombotic or bleeding complications.
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Introduction: Limited data exist on long-term follow-up of severe aortic stenosis (SAS) patients who have undergone transcatheter aortic valve implantation (TAVI) with a new generation, balloon expandable Myval transcatheter heart valve (THV). Thus, we sought to investigate the performance and 2-year clinical outcome of the Myval THV system based on Valve Academic Research Consortium-3 (VARC-3) criteria.

Material And Methods: A multi-centre, registry-based, observational study was conducted, which included 207 consecutive degenerative SAS patients, from Turkey ( = 128), Italy ( = 58), and Greece ( = 21) (mean [standard deviation] 81 (7) years, 94 [45%] men; 73% NYHA III or IV; EuroSCORE II 5.

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Purpose: To evaluate the choroidal vascularity index and choroidal thickness in patients with rheumatoid arthritis.

Method: This study is a case control study. Our study consists of a total of two groups, with 32 individuals diagnosed with rheumatoid arthritis (RA) and 32 healthy volunteers.

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Introduction: The correlation between non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease is well established.

Aim: The objective of this study was to assess the short-term associations of the non-alcoholic fatty liver disease fibrosis score (NFS) with various outcomes, including mortality, severe coronary artery disease, myocardial infarction, and the need for coronary angiography, among patients who underwent coronary computed tomographic angiography (CCTA).

Material And Methods: In this study, we assessed 499 patients who underwent 640-slice CCTA and evaluated their liver fibrosis using the NFS.

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Study Design: Retrospective clinical study.

Objectives: We aimed to investigate preoperative spinopelvic mismatch as a risk factor for recurrent lumbar disk herniation (RLDH) in patients undergoing lumbar disk herniation (LDH) surgery.

Summary Of Background Data: Spinopelvic parameters have been associated with lumbar degenerative diseases, particularly LDH.

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Background: There are various changes in cardiac physiology in athletes compared to the normal population. These physiological changes may differ according to the exercise content. The aim of this study was to compare the effects of different exercise methods on the heart.

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Article Synopsis
  • A 66-year-old man was hospitalized with symptoms like abdominal pain and fever, ultimately diagnosed with acute emphysematous aortitis after CT scans showed significant abnormalities in the aorta.* -
  • Despite starting antibiotic treatment, his condition worsened, leading to the discovery of a mycotic aneurysm, prompting the heart team to recommend urgent surgery, which the patient declined due to high risks.* -
  • Instead, an endovascular stent-graft was successfully implanted, the patient completed an 8-week antibiotic course, and eventually discharged in good health, highlighting the importance of recognizing aortitis in patients with specific symptoms.*
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Bicuspid aortic valve is the most common congenital cause for the development of aortic valve calcification and stenosis. Calcification cause valvular stenosis or valvular insufficiency due to coaptation failure. We report a unique case of calcification of bicuspid valve was extending to left ventricular outflow tract and attached to interventricular septum which caused subvalvular stenosis.

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Background: The study aimed to assess the impact of percutaneous transcatheter atrial septal defect (ASD) closure on atrium and atrial appandage functions among patients with ostium secundum ASDs.

Methods: A total of 101 patients (34,7% male, 65,3% female, 37,6 ± 12) with the diagnosis of ostium secundum type ASD underwent transthorasic (TTE) and transesophageal echocardiography (TEE) before and six months after percutaneous transcatheter ASD closure. Pulmonary venous flow and atrial appendage flow velocities were obtained from the TEE recordings.

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Methods: A total of 197 patients (102 patients with CSF; 95 patients with normal coronary flow) were included in this retrospective study. Clinical and angiographic characteristics of patients were obtained from hospital records.

Results: Patients with CSF had higher SII, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), and high-sensitivity C-reactive protein (hsCRP) levels compared with the control group.

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Objectives: To investigate and determine the choroidal thickness (CT) in healthy emmetropic Turkish subjects aged between 20 and 40 years using Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography (EDI-OCT).

Methods: This study included 194 eyes of 194 healthy emmetropic subjects. All participants underwent a detailed ophthalmologic examination.

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Purpose: To investigate the choroidal vascularity index (CVI) and morphological features of the choroid in anisometropic amblyopia.

Methods: In this prospective cross-sectional study, 39 patients with unilateral anisometropic amblyopic patients and 33 eyes of 33 healthy control participants were involved. These participants were examined in terms of axial length (AL), spherical equivalent (SE), central macular thickness (CMT), choroidal thickness (CT), total choroidal area (TCA), luminal area (LA), stromal area (SA), LA/SA ratio, and CVI.

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Background: The distance between the optic disc center and the fovea is a biometric parameter; however, it is unclear whether DFD (disc-fovea distance) affects the choroidal thickness.

Objective: The aim of this study is to investigate the association between DFD and choroidal thickness.

Design: This is a prospective, and cross-sectional study.

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Introduction: Alopecia areata (AA) is an autoimmune disease which causes non-scarring type hair loss considered to target the pigmentary system. The hair follicle may not be the only site for involvement of the disease. Iris, the ciliary body, choroid and epithelium of the retinal pigment may also be affected.

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Introduction: This study aims to compare the choroidal thickness (CT) of patients with rosacea with healthy individuals.

Methods: This study was conducted with 42 patients with Papulopustular Rosacea (PPR), 38 patients with Erythematotelangiectatic Rosacea (ETR), and gender and age-matched 37 healthy individuals in the control group. CT measurements were done using the spectral-domain optical coherence tomography.

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Purpose: To evaluate structural changes in the anterior chamber and intraocular pressure (IOP) changes following intravitreal dexamethasone implantation.

Methods: Forty-two eyes of 42 patients that received intravitreal dexamethasone implant for the management of macular edema secondary to diabetic retinopathy or branch retinal vein occlusion (BRVO) were included in the study. IOP was measured by Goldmann applanation tonometry.

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Purpose: To compare the ciliary muscle thickness (CMT) of the normal fellow eye to that of the amblyopic eye using ultrasound biomicroscopy (UBM) in patients with unilateral anisometropic amblyopia.

Methods: Thirty patients with unilateral anisometropic amblyopia were involved. The patients were divided into two groups: 19 hyperopic and 11 myopic.

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Aim: This study aimed to explore the role of peritoneal ultrafiltration (UF) in cardiorenal syndrome (CRS) patients for fluid and metabolic control.

Background: Peritoneal UF is safely and efficiently used for the management of CRS. It has been shown to provide efficient UF in hypervolemic patients.

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Background/objective: The aim was to evaluate the left and right ventricular functions concurrently by two-dimensional speckle tracking echocardiography (STE) in systemic sclerosis (SSc) patients without overt cardiac disease.

Methods: A total of 47 patients with SSc and 36 age- and sex-matched controls were evaluated cross-sectionally. Two-dimensional STE was used to assess the longitudinal peak systolic strains (PSS) of both ventricles including apical long-axis (APLAX), apical four-chamber (4-CH), apical two-chamber (2-CH), and global longitudinal measurements.

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Systemic sclerosis is associated with an increased prevalence/incidence of coronary artery disease. The aim of this study was to investigate epicardial adipose tissue (EAT) thickness which may contribute to cardio-metabolic risk in systemic sclerosis (SSc) patients without overt cardiac disease. EAT thickness was measured by transthoracic conventional Doppler echocardiography and compared in SSc patients (n = 47) and age- and sex-matched healthy controls (n = 36).

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Objective: The aim of this study was to determine the relationship of left atrial appendage (LAA) mechanics assessed using 2-dimensional (2D)-strain analysis of the gray scale images obtained during transesophageal echocardiography (TEE) to the conventional LAA functional parameters, CHA2DS2-VASc score, and the presence of spontaneous echo contrast (SEC) and/or LAA thrombus in patients with non-valvular atrial fibrillation (AF).

Methods: The study included 126 patients with AF and 30 controls with a sinus rhythm who were referred for TEE. The global, medial, lateral and apical LAA longitudinal 2D-strain of all patients and the CHA2DS2-VASc score of AF patients were evaluated.

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