Publications by authors named "Tayebeh Vaezi"

Article Synopsis
  • - The research indicates that different variants of HPV 16, particularly lineages A and D, vary in their potential to cause cancer and their geographic distribution, emphasizing the importance of studying these regional variants.
  • - In a study of 106 HPV 16 isolates, lineage D was found to be predominant, making up 70.7% of the samples, while lineage A comprised 29.3%, with lineage D also dominant in both normal and precancerous cervical conditions.
  • - Although lineage A appeared more frequently in cervical cancer cases (20% in normal+CIN I-II vs. 33.8% in CIN III+ICC), the difference was not statistically significant, reinforcing the higher prevalence of lineage D in Iran
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In Iran, human papillomavirus (HPV) vaccination is not currently included in the national vaccination program and there are no comprehensive approaches to cervical screening program. Regional data on distribution of HPV types in women is important to predict the impact of current HPV vaccines. Although several studies on distribution of HPV types in cervical precancer and cancer have been conducted in Iran, in most of them HPV positive samples were subjected to specific-primer genotyping (mainly 16 and 18), and leaving the other HPV genotypes almost undetermined.

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