Publications by authors named "Tayebeh Jafari-Nasab"
The considerable flexibility of cancerous cells to escape from chemical and biological drugs makes it clear that much is to be done to control and eliminate such cells. Probiotic bacteria, in this regard, have shown promising performance. In this study, we isolated and characterized lactic acid bacteria from traditional cheese.
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- Eighteen lactic acid bacteria were isolated from traditional dairy products, showing strong probiotic potential, especially strain M1.
- Strain M1 was identified through 16S rRNA gene sequencing, displaying notable antipathogenic activity without significant antibiotic resistance and resilience to high bile salt, salt, and low pH conditions.
- The cell-free supernatant from M1, along with its heat-killed and live cells, caused 85% cell death in MCF-7 cancer cells by promoting apoptosis, as indicated by changes in BAX and Bcl-2 protein levels.