Publications by authors named "Tay W"

The entomopathogenic fungus infects diverse insect host species. We present an annotated draft genome of (Commonwealth Scientific and Industrial Research Organisation [CSIRO] strain M-1000) isolated from a species individual, thereby contributing to future research of as a potential biological control agent.

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Introduction: The safety of continuing anticoagulation therapy during endoscopic variceal ligation (EVL) remains controversial. We performed a systematic review and meta-analysis to evaluate the safety of anticoagulation therapy in EVL.

Methods: We systematically searched four electronic databases from their inception until 1 June 2024, for studies that evaluated anticoagulation use and risk of rebleeding among patients undergoing EVL.

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Background: Helicoverpa armigera is a highly polyphagous species that causes huge losses to agricultural and horticultural crops worldwide. In the cotton industry, H. armigera, including the Australian subspecies Helicoverpa armigera conferta, is largely managed using genetically modified crops that express insecticidal toxins, such as Cry1Ac.

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Background: Outcomes of hospitalized patients with heart failure (HF) and characteristics of advanced HF stage may vary across left ventricular ejection fraction (LVEF) and world regions.

Objectives: This study sought to analyze characteristics of hospitalized advanced HF patients across LVEF spectrum, world regions, and country income.

Methods: Among 18,553 hospitalized patients with acute HF (7,902 new-onset HF and 10,651 decompensated chronic HF) enrolled in the global registry REPORT-HF (International Registry to Assess Medical Practice With Longitudinal Observation for Treatment of Heart Failure), we analyzed characteristics and outcomes of patients with advanced HF, defined as previously diagnosed HF; severe symptoms before current admission (NYHA functional class III/IV); and ≥1 HF-related hospitalization in the preceding 12 months, excluding the current.

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Background: Cone-beam computed tomography (CBCT) provides additional 3-dimensional information on the relationship between the mandibular third molar (M3M) and the inferior alveolar nerve (IAN). As such, CBCT is being increasingly utilized in preoperative M3M assessment.

Purpose: The purpose of the study was to compare the radiographic findings on panoramic and CBCT and their association with postoperative IAN paresthesia.

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Article Synopsis
  • - The report discusses a patient who came to the Emergency Department with breathing issues, weakness, trouble swallowing, and walking difficulties after receiving cosmetic botulinum toxin injections.
  • - She self-administered 100 units of onabotulinumtoxin A (BoNT-A) injections in her face two weeks before her symptoms appeared.
  • - The case emphasizes the rare risk of systemic botulism as a complication following cosmetic botulinum toxin use.
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Article Synopsis
  • The study examined heart failure patients with initially low ejection fractions who later showed improvement, identifying about 20% of these individuals achieving a significant increase in heart function after 9 months.* -
  • Patients with improved ejection fraction experienced lower rates of rehospitalization and mortality compared to those with persistently low function, with consistent results found in two separate patient registries.* -
  • Five key predictors for improvement were identified: female sex, absence of ischemic heart disease, higher initial ejection fraction, and smaller heart sizes, allowing the development of a predictive model to better assess who may improve.*
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Multiple Epiphyas species inhabit southwestern Western Australia, including Light Brown Apple Moth (LBAM) Epiphyas postvittana (Walker) (Lepidoptera: Tortricidae), a globally significant, polyphagous pest. This study evaluated the efficacy and specificity of lures designed for 3 Epiphyas species: E. postvittana, Epiphyas pulla (Turner), and the undescribed Epiphyas sp.

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Article Synopsis
  • The research evaluates the shift from traditional clinical trial design for heart failure (HF) to a data-driven approach, utilizing natural language processing to analyze trial eligibility criteria.
  • Phase III trials for HF were examined to identify common inclusion and exclusion criteria, finding that only about 20% of registry patients were eligible for these trials.
  • Over time, the trials have become more restrictive, with a significant decline in patient eligibility from 40% in earlier years to 19% in recent years, highlighting the need for a better design framework for future trials.
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  • The study aimed to explore how serial measurements of NT-proBNP, a heart failure biomarker, relate to cardiac changes and patient outcomes, considering various clinical factors.
  • Analysis involved 1911 heart failure patients, revealing that NT-proBNP levels generally declined, especially in certain groups like inpatients and those on guideline-recommended medications.
  • An increase in NT-proBNP over time was linked to a higher risk of hospitalization or death, with variations noted based on patient age, atrial fibrillation presence, and heart failure types.
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Although a rich academic literature examines the use of fake news by foreign actors for political manipulation, there is limited research on potential foreign intervention in capital markets. To address this gap, we construct a comprehensive database of (negative) fake news regarding U.S.

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Aims: Hospital readmissions due to recurrent fluid overload in diabetes and diabetic kidney disease can be avoided with evidence-based interventions. We aimed to identify at-risk patients who can benefit from these interventions by developing risk prediction models for readmissions for fluid overload in people living with diabetes and diabetic kidney disease.

Methods: This was a single-center retrospective cohort study of 1,531 adults with diabetes and diabetic kidney disease hospitalized for fluid overload, congestive heart failure, pulmonary edema, and generalized edema between 2015 and 2017.

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The physics governing the fluid dynamics of bio-inspired flapping wings is effectively characterized by partial differential equations (PDEs). Nevertheless, the process of discretizing these equations at spatiotemporal scales is notably time consuming and resource intensive. Traditional PDE-based computations are constrained in their applicability, which is mainly due to the presence of numerous shape parameters and intricate flow patterns associated with bionic flapping wings.

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Surfactant/polymer flooding allows for a significant increase in oil recovered at both laboratory and field scales. Limitations in application at the reservoir scale are, however, present and can be associated with both the complexity of the underlying displacement process and the time-intensive nature of the up-scaling workflow. Pivotal to this workflow are corefloods which serve to both validate the extent of oil recovery and extract modeling parameters used in upscaling.

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Nanoparticles as cancer therapeutic carrier fail in clinical translation due to complex biological environments in vivo consisting of electrolytes and proteins which render nanoparticle aggregation and unable to reach action site. This review identifies the desirable characteristics of nanoparticles and their constituent materials that prevent aggregation from site of administration (oral, lung, injection) to target site. Oral nanoparticles should ideally be 75-100 nm whereas the size of pulmonary nanoparticles minimally affects their aggregation.

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A 58-year-old woman with poorly controlled diabetes, peripheral vascular disease, and end-stage renal disease requiring hemodialysis was referred for 18 F-FDG PET/CT to evaluate for source of sepsis. She had history of prior left forefoot and right second toe amputation, as well as left lower-limb dry gangrene for which she declined surgical management. We present a case of a nonamputated lower limb demonstrating regions of absolute photopenia, consistent with dry gangrene.

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Article Synopsis
  • Heart failure with normal ejection fraction (HFnEF) is relatively unexplored compared to other forms of heart failure, prompting researchers to study its characteristics and outcomes.
  • In a study of 1,765 patients, a significant portion had HFnEF, distinguishing them from those with preserved but low ejection fraction by factors like lower coronary artery disease rates and differing echocardiographic patterns.
  • Understanding the varied cardiac features among HFnEF patients might help develop more tailored treatment strategies for those with heart failure with preserved ejection fraction (HFpEF).
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