Publications by authors named "Tay Bee Yong"
Article Synopsis
- Human brucellosis is a neglected zoonotic disease that occurs in various locations around the world.
- In Malaysia, there have been both outbreaks and isolated cases of this disease.
- This study presents the whole-genome sequences of four strains of the bacteria isolated from patients suffering from brucellosis in Malaysia.
Article Synopsis
- Brucellosis, a common zoonotic disease, poses a significant health issue globally, particularly in Malaysia where human brucellosis studies and genetic analysis are scarce.
- The study analyzed 43 Brucella melitensis and 2 Brucella suis isolates over six years using multiple-locus variable-number tandem-repeat analysis (MLVA), revealing low genetic diversity with a predominance of genotypes linked to the East Mediterranean group.
- This research is the first of its kind in Malaysia, highlighting the importance of B. melitensis in local Brucella infections and providing a foundation for future studies on the disease's genetic diversity.
Molecular approaches have been investigated to overcome difficulties in identification and differentiation of Brucella spp. using conventional phenotypic methods. In this study, high-resolution melt (HRM) analysis was used for rapid identification and differentiation of members of Brucella genus.
View Article and Find Full Text PDF