* An 81-year-old man with an arteriovenous fistula (AVF) presented with an aggressive form of well-differentiated metastatic SCC, leading to the necessity of an axillary lymph node dissection after excising the primary cancer.
* The combination of factors such as immunosuppression, chronic inflammation, and trauma to the AVF contributed to the aggressive nature of SCC in this patient, highlighting the need for careful monitoring and management of skin cancers in individuals