Genomic findings of hypertrophic and dilated cardiomyopathy characterized in a Thai clinical genetics service.

Hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) are the most common referrals in the Inherited Cardiovascular Condition (ICC) Genetics Service. Several issues must be discussed with patients and their families during the genetic consultation session, including the options for genetic testing and cardiovascular surveillance in family members. We developed an ICC registry and performed next-generation-based DNA sequencing for all patients affected by non-syndromic HCM and idiopathic DCM in our joint specialist genetics service.

Transcatheter tricuspid valve-in-valve implantation for degenerative surgical bio-prosthesis using SAPIEN 3: A case series.

We evaluated early outcomes of transcatheter valve-in-valve (ViV) implantation in patients with degenerated bio-prosthesis in tricuspid position. Total of 5 patients were included in our case series. Baseline native tricuspid valve etiology were highly varied ranging from chest wall trauma, Ebstein anomaly, rheumatic heart disease, infective endocarditis and complex congenital heart disease.

Type A aortic dissection presenting as acute ischemic stroke caution for thrombolytic therapy: a case report and literatures review.

The authors reported a patient who had type A aortic dissection presenting with sudden onset of right hemiplegia and depressed consciousness. CT scan of brain showed acute cerebral infarction of left corona radiata, posterior limb of left internal capsule combined with left hemispheric brain swelling. An old cerebral infarction at the posterior limb of right internal capsule was also noted Clinical signs of aortic regurgitation and difference in blood pressures and amplitude of pulses on both arms were associated.