Sustainable livelihood capital and climate change adaptation in Pakistan's agriculture: Structural equation modeling analysis in the VIABLE framework.

This study aims to assess the role of sustainable livelihood capital, the mediation of investments and farming purposes, and the moderation of climatic and non-climatic factors in the adaptation process, particularly in the aspects of Crop, Farm, Irrigation, and Economic Management. Moreover, guided by the VIABLE (Values and Investments for Agent-Based Interaction and Learning in Environmental Systems) framework, we analyze stakeholders' actions, priorities, and goals in the climate change adaptation process. A structured questionnaire was designed based on a five-point Likert scale covering the concepts of livelihood capital, climate change adaptation, investment priorities, farming constraints, and farmers' decision-making factors.

Environmental sustainability and green technologies across BRICS countries: the role of institutional quality.

In recent years, a growing body of research has focused on the environment and economic growth nexus. However, there has not been much research done on how environmentally friendly technologies and institutional quality affect pollution levels. It is found that in developed countries, the rate of environmental deterioration has slowed thanks to more sustainable environmental regulations, advances in technology, and improvements in the quality of institutions.

Conversion of adverse data corpus to shrewd output using sampling metrics.

An imbalanced dataset is commonly found in at least one class, which are typically exceeded by the other ones. A machine learning algorithm (classifier) trained with an imbalanced dataset predicts the majority class (frequently occurring) more than the other minority classes (rarely occurring). Training with an imbalanced dataset poses challenges for classifiers; however, applying suitable techniques for reducing class imbalance issues can enhance classifiers' performance.

Synthesis, characterization, molecular docking, analgesic, antiplatelet and anticoagulant effects of dibenzylidene ketone derivatives.

In this study dibenzylidene ketone derivatives (2E,5E)-2-(4-methoxybenzylidene)-5-(4-nitrobenzylidene) cyclopentanone (AK-1a) and (1E,4E)-4-(4-nitrobenzylidene)-1-(4-nitrophenyl) oct-1-en-3-one (AK-2a) were newly synthesized, inspired from curcuminoids natural origin. Novel scheme was used for synthesis of AK-1a and AK-2a. The synthesized compounds were characterized by spectroscopic techniques.

Resolution of ipilimumab induced severe hepatotoxicity with triple immunosuppressants therapy.

We describe a case of a patient from Far North Queensland, Australia, with life-threatening hepatotoxicity caused by ipilimumab induced immune-related adverse events (irAEs). Our patient presented with non-specific symptoms including malaise, lethargy and fevers. Her work up revealed acute hepatitis, which was presumed to be related to ipilimumab treatment for her metastatic melanoma.

Severity of Plasmodium vivax malaria in Karachi: a cross-sectional study.

Introduction: Plasmodium vivax malaria affects billions of people annually. This study aimed to note the presentations and complications and subsequently to identify the determinants of in-patient hospital care of P. vivax malaria patients presenting to a tertiary care hospital in Karachi, Pakistan.