Gliomas are the most common neuroepithelial brain tumors, different by various biological tissue types and prognosis. They could be graded with four levels according to the 2007 WHO classification. The emergence of non-invasive histological and molecular diagnostics for nervous system neoplasms can revolutionize the efficacy and safety of medical care and radically reduce healthcare costs.
View Article and Find Full Text PDFThe possibility of postoperative speech dysfunction prediction in neurosurgery based on intraoperative cortico-cortical evoked potentials (CCEP) might provide a new basis to refine the criteria for the extent of intracerebral tumor resection and preserve patients' quality of life. In this study, we aimed to test the quality of predicting postoperative speech dysfunction with machine learning based on the initial intraoperative CCEP before tumor removal. CCEP data were reported for 26 patients.
View Article and Find Full Text PDFBackground: The role of soil invertebrates in the cycle of substances, soil-forming processes and the provision of ecosystem services is undeniable. Therefore, soil invertebrates are valuable in bioindication studies. Comprehensive research of soil invertebrates in the production area of Mondi Syktyvkar JSC as the largest pulp and paper enterprise in the European part of Russia was initiated in 2003.
View Article and Find Full Text PDFBackground: The purpose of the data paper was to introduce into scientific literature the results of scientific work carried out for the third edition of the 'Red Data Book of the Komi Republic'. The article reflects methodological approaches to the formation of a list of rare and in need of protection species and describes the corresponding datasets published in GBIF.
New Information: Information about 7,187 occurrences of 438 rare species and infraspecies included in the third edition of the 'Red Data Book of the Komi Republic' have been published.
Background: The European North-East of Russia is the territory which includes the Nenets Autonomous District, represented by the East European tundra (from Kanin Peninsula to Vaigach Island), Komi Republic with its taiga ecosystems and the Urals (Northern, SubPolar and Polar). Over 20 years of systematic studies of soil fauna in the studied region has resulted in a huge amount of data being accumulated that can be analysed from different positions. Considering that the representation of Russian soil biota data, especially from European North-East of Russia in the GBIF database is not large, our data are of great interest to the scientific world community.
View Article and Find Full Text PDFThe terrestrial environment of the East European tundra consists of a mosaic of habitat types. In addition to the natural habitat diversity, various human-influenced types may occur. In the town of Vorkuta, Komi Republic, Russia the manure-enriched soils near hydrogen sulfide springs were observed.
View Article and Find Full Text PDFBackground: Experimental data accumulated over more than a decade indicate that cross-strain protection against influenza may be achieved by immunization with conserved influenza proteins. At the same time, the efficacy of immunization schemes designed along these lines and involving internal influenza proteins, mostly NP and M1, has not been sufficient.
Objective: To test the immunogenicity and protective efficacy of DNA vaccination with a combination of NP, M1 and NS1 genes of influenza virus.