Oral application of carbon nanofibers in rats increases blood concentration of IL6 and IL10 and decreases locomotor activity.

Carbon nanofibers (CNF) are versatile nanomaterials that are widely used in various fields of science and technology. As a consequence, animals as well as humans may be exposed to such compounds via different routes. We hypothesized that oral intake of CNF will lead to an inflammatory reaction and consequently induce behavioral impairments.

Influence of multi-walled carbon nanotubes on the cognitive abilities of Wistar rats.

Studies of the neurobehavioral effects of carbon nanomaterials, particularly those of multi-walled carbon nanotubes (MWCNTs), have concentrated on cognitive effects, but data are scarce. The aim of this study was to assess the influence of MWCNTs on a number of higher nervous system functions of Wistar rats. For a period of 10 days, two experimental groups were fed with MWCNTs of different diameters (MWCNT-1 group, 8-10 nm; MWCNT-2 group, 18-20 nm) once a day at a dosage of 500 mg/kg.