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Publications by authors named "Tatusya Ando"

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Administration of spermidine attenuates concanavalin A-induced liver injury.
Tatusya Ando Daisuke Ito Kazuya Shiogama Yasuhiro Sakai Masato Abe

Biochem Biophys Res Commun

March 2023

A previous study revealed that treatment with the anticoagulant heparin attenuated concanavalin A (ConA)-induced liver injury. The administration of spermidine (SPD) increased urokinase-type plasminogen activator (uPA) levels in the serum. uPA is clinically used for the treatment of some thrombotic diseases such as cerebral infarction.

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Synopsis of recent research by authors named "Tatusya Ando"

  • - Tatusya Ando's recent research primarily focuses on the therapeutic effects of spermidine in liver injury models, particularly in the context of concanavalin A-induced liver damage.
  • - The 2023 study published in "Biochemical and Biophysical Research Communications" demonstrates that spermidine administration elevates levels of urokinase-type plasminogen activator (uPA) in the serum, suggesting potential therapeutic pathways.
  • - The findings contribute to the understanding of spermidine as a valuable agent not only in liver protection but also potentially in treating thrombotic conditions, reinforcing its clinical relevance in medicine.

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