Effect of Inspiratory Muscle Training on Cough Strength in Older People With Frailty: A Single-Blind Randomized Controlled Trial.

Objective: To investigate the effect of inspiratory muscle training (IMT) on cough strength in older people with frailty.

Design: Single-blind randomized controlled trial.

Setting: Day health care centers at 2 sites.

Programmable molecular transport achieved by engineering protein motors to move on DNA nanotubes.

Intracellular transport is the basis of microscale logistics within cells and is powered by biomolecular motors. Mimicking transport for in vitro applications has been widely studied; however, the inflexibility in track design and control has hindered practical applications. Here, we developed protein-based motors that move on DNA nanotubes by combining a biomolecular motor dynein and DNA binding proteins.

Early walking time is associated with recovery of activities of daily living during hospitalization in older patients with community-acquired pneumonia: A single-center prospective study.

Aim: Pneumonia is a common disease with a high mortality rate among older adults that is associated with a decline in activities of daily living (ADL) during hospitalization. The aims of this study were to investigate the following: (i) early physical activity time among older patients hospitalized with community-acquired pneumonia; and (ii) the association of physical activity time with the recovery of ADL.

Methods: A prospective observational study was carried out in patients aged ≥65 years hospitalized with community acquired pneumonia.