Diffuse Alveolar Hemorrhage Due to Macrolide-Refractory Mycoplasma pneumoniae Diagnosed by FilmArray Analysis of Bronchoalveolar Lavage Fluid.

typically causes mild respiratory infections but can rarely lead to severe complications. We report a case of a 43-year-old immunocompetent male who presented with progressive dyspnea and respiratory failure with bilateral pulmonary infiltrates, refractory to outpatient treatment with azithromycin, ceftriaxone, and levofloxacin. Bronchoscopy revealed multiple white plaques in the trachea and diffuse alveolar hemorrhage.

Inhibitory Effects of Auraptene and Naringin on Astroglial Activation, Tau Hyperphosphorylation, and Suppression of Neurogenesis in the Hippocampus of Streptozotocin-Induced Hyperglycemic Mice.

Auraptene, a citrus-related compound, exerts anti-inflammatory effects in peripheral tissues, and we demonstrated these effects in the brains of a lipopolysaccharide-injected systemic inflammation animal model and a brain ischemic mouse model. Naringin, another citrus-related compound, has been shown to exert antioxidant effects in several animal models. Hyperglycemia induces oxidative stress and inflammation and causes extensive damage in the brain; therefore, we herein evaluated the anti-inflammatory and other effects of auraptene and naringin in streptozotocin-induced hyperglycemic mice.