Synopsis of recent research by authors named "Tatsuki Fukami"
Recent research by Tatsuki Fukami focuses on the enzymatic processes involved in drug metabolism, particularly in the human liver and kidney, as well as the implications for therapeutic efficacy and safety.
His studies highlight the roles of various enzymes such as arylacetamide deacetylase and cytochrome P450 in the formation of key metabolites from drugs used to treat conditions like idiopathic pulmonary fibrosis and their impact on drug pharmacokinetics.
Additionally, Fukami explores the molecular mechanisms of enzyme regulation and the interaction of nuclear receptors with cellular components, shedding light on how these interactions influence drug metabolism and potential drug-drug interactions.