Publications by authors named "Tatsuhiro Ishimura"
Background And Objectives: The choice between inhalational and total intravenous anesthesia (TIVA) in revascularization surgery for Moyamoya disease (MMD) remains a topic of debate. Anesthesia methods have changed with the advent of new anesthetics. This study investigated whether modern anesthesia methods affected the development of neurological symptoms after revascularization surgery for MMD.
View Article and Find Full Text PDFBackground: Evaluating patients' risk for acute kidney injury (AKI) is crucial for positive outcomes following cardiac surgery. Our aims were first to select candidate risk factors from pre- or intra-operative real-world parameters collected from routine medical care and then evaluate potential associations between those parameters and risk of onset of post-operative cardiac surgery-associated AKI (CSA-AKI).
Method: We conducted two cohort studies in Japan.
Article Synopsis
- N-acetylaspartylglutamate (NAAG) is a key neurotransmitter that activates mGluR3 and is broken down by GCPII, a target for pain relief.
- Inhibitors of GCPII have shown effectiveness in reducing various types of pain, including inflammatory and neuropathic pain, by modulating noradrenaline release in the locus coeruleus.
- The analgesic effects of GCPII inhibitors involve multiple receptor systems, including group II mGluR, AMPA, and alpha 2 adrenergic receptors, particularly impacting the contralateral locus coeruleus.
Background: The pin-index medical gas pipeline system, which complies with Japan Industrial Standard (JIS), is considered to be "foolproof" and is widely used in Japan to avoid medical gas misconnections.
Case Presentation: The wall-mounted gas outlet used in our hospital (NSV outlet, CENTRAL UNI, Co., Ltd.
Purpose: This study was undertaken to establish a model to predict the post-operative mortality for emergency surgeries.
Methods: A regression model was constructed to predict in-hospital mortality using data from a cohort of 479 cases of emergency surgery performed in a Japanese referral hospital. The discrimination power of the current model termed the Calculation of post-Operative Risk in Emergency Surgery (CORES), and Portsmouth modification of the Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (P-POSSUM) were validated using the area under the receiver operating characteristic curve (AUC) in another cohort of 494 cases in the same hospital (validation subset).