Clinicopathological Correlations of Autophagy-related Proteins LC3, Beclin 1 and p62 in Gastric Cancer.

Aim: This study evaluated the clinicopathological significance of autophagy, an intracellular degradation system, in gastric cancer.

Materials And Methods: The expression levels of three autophagy-related proteins, namely light chain 3 (LC3), Beclin 1 and p62, were analyzed by immunohistochemistry using samples from 510 patients with primary gastric cancer.

Results: LC3, Beclin 1, and p62 expression was positive in 79 (15.