Publications by authors named "Tatjana Madic"
Article Synopsis
- The European Society of Gynaecological Oncology and other organizations created consensus statements to enhance care for patients with vaginal intraepithelial neoplasia (VaIN).
- Treatment for VaIN depends on the lesion's grade, with follow-ups for low-grade VaIN (VaIN 1) and treatment required for high-grade (VaIN 2-3), highlighting that management should be personalized.
- Surgical excision is the primary treatment; alternatives like CO laser and topical agents exist, with imiquimod showing the best outcomes, while brachytherapy is suited for specific cases, and consistent follow-up is essential due to the recurring nature of VaIN.
Article Synopsis
- The consensus statements developed by ESGO, ISSVD, ECSVD, and EFC aim to enhance care for patients with vaginal intraepithelial neoplasia (VaIN), outlining management strategies based on lesion grade.
- For low-grade VaIN (VaIN 1), follow-up is usually sufficient, while high-grade VaIN (VaIN 2-3) requires treatment, with surgical excision being the primary method if invasion is suspected.
- Treatments like CO2 laser and topical agents, especially Imiquimod, are effective, but surgical options are often necessary for cases post-hysterectomy, and patients should be closely monitored due to the risk of recurrence.
Polycystic ovary syndrome (PCOS) is a frequent endocrine disease in women during the reproductive period. It is considered a complex metabolic disorder with long-term metabolic, as well as reproductive consequences. Main pathophysiological pathways are related to the increased androgen levels and insulin resistance.
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