Rheological properties of blood and parameters of platelets aggregation in arterial hypertension.

The results of some researches specify the important role of blood rheological properties changes in arterial hypertension (AH) pathogenesis. The goal of our study is to investigate the parameters of hemorheology and platelet aggregation in patients with various grade of AH. The study was carried out on 27 patients with grade 1 AH (group 1), 24 patients with grade 2 AH (group 2) and 29 healthy subjects (group 3).

Plasma lipid levels, blood rheology, platelet aggregation, microcirculation state and oxygen transfer to tissues in young and middle-aged healthy people.

It has been reported that dyslipidemia is associated with rheological and microcirculatory abnormalities in patients with ischaemic heart disease. However, it is not known how this system changes in men and women with ageing. In healthy young and middle-aged subjects the following parameters were evaluated: total plasma cholesterol, triglycerides and HDL-cholesterol levels, deformability of erythrocytes, red blood cell and platelet aggregations, blood and plasma viscosity, neutrophils' cytosolic [Ca2+]i and microviscosity of the bilayer's total lipid phase and the annular near-protein zone of the membranes.