Publications by authors named "Tatiana Zueva"
Article Synopsis
- The study compares how full-length PML isoforms and their C-terminal domains form PML bodies with and without endogenous PML, identifying key characteristics of these structures.
- Findings show that full-length PML isoforms can independently create dynamic liquid-droplet compartments, while only specific C-terminal domains (of PML-II and PML-V) can incorporate into endogenous PML bodies.
- Moreover, alterations like the K490R substitution affect the distribution of these domains in cells, emphasizing the importance of disordered regions in facilitating liquid-liquid phase separation, regardless of the presence of structured N-terminal motifs.
Background: Angiogenesis can occur under pathological conditions when stimuli such as inflammation, vascular obstruction or hypoxia exist. These stimuli are present in cardiopulmonary dirofilariosis (Dirofilaria immitis). The aim of this study was to analyze the capacity of D.
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