Publications by authors named "Tatiana Vasilieva"

The applicability of beam-plasma chemical reactors generating cold hybrid plasma for the production of noncytotoxic polymeric surfaces with high hydrophilicity and good biocompatibility with human fibroblast culture and human red blood cells was studied. Oxygen hybrid plasma was excited by the joint action of a continuous scanning electron beam and a capacity-coupled RF-gas discharge. Experiments showed that hybrid plasma treatment caused polar oxygen-containing functional group formation in the surface layer of poly (ethylene terephthalate) films.

View Article and Find Full Text PDF

Background: Today, genomic changes are an important cause of the occurrence, growth and progression of cancer. Technological advances in cancer genomic analysis platforms have made it possible to identify genomic alterations that may influence response to lung cancer treatment.

Methods: The study examined tumor growth-inhibiting oncogenes and genes responsible for cell growth and division to identify mutations characteristic of malignant lung tumors.

View Article and Find Full Text PDF
Article Synopsis
  • Metformin is commonly used to treat type 2 diabetes, but individual responses to the drug can vary significantly, potentially due to genetic differences.
  • A study analyzed the effects of specific genetic variants on metformin response in 299 patients, identifying the rs12208357 variant as significantly impacting treatment outcomes.
  • Machine learning models incorporating genetic and clinical factors, like gender and body measurements, were developed to better predict metformin response, showing potential for personalized diabetes treatment approaches.
View Article and Find Full Text PDF

Polysaccharide processing by means of low-temperature Electron Beam Plasma (EBP) is a promising alternative to the time-consuming and environmentally hazardous chemical hydrolysis in oligosaccharide production. The present paper considers mechanisms of the EBP-stimulated destruction of crab shell chitin, cellulose sulfate, and microcrystalline cellulose, as well as characterization of the produced oligosaccharides. The polysaccharide powders were treated in oxygen EBP for 1-20 min at 40 °C in a mixing reactor placed in the zone of the EBP generation.

View Article and Find Full Text PDF