Background: Previous work on endothelial dysfunction in post-MI heart failure has shown conflicting results.
Aim: To analyze gender related alterations in NO-, PGI(2)- and EDHF-dependent endothelial function in the thoracic aorta 7 and 42 days after myocardial infarction (MI).
Methods And Results: MI was induced by coronary artery ligation in female and male Sprague-Dawley rats.