[Atrial fibrillation and dementia: not everything is clear…].

The prevalence of dementia is ever increasing, as well as the prevalence of atrial fibrillation (AF). Several studies and systematic reviews evaluated the association between AF and dementia, highlighting an increased risk for dementia (with odds ratios from 1.4 to 1.

Transcranial Doppler sonography for detecting stenosis or occlusion of intracranial arteries in people with acute ischaemic stroke.

Background: An occlusion or stenosis of intracranial large arteries can be detected in the acute phase of ischaemic stroke in about 42% of patients. The approved therapies for acute ischaemic stroke are thrombolysis with intravenous recombinant tissue plasminogen activator (rt-PA), and mechanical thrombectomy; both aim to recanalise an occluded intracranial artery. The reference standard for the diagnosis of intracranial stenosis and occlusion is intra-arterial angiography (IA) and, recently, computed tomography angiography (CTA) and magnetic resonance angiography (MRA), or contrast-enhanced MRA.

Sonothrombolysis for acute ischaemic stroke.

Background: Sonothrombolysis is a promising but unproven tool for treating acute ischaemic stroke. There is an ongoing debate about the efficacy, safety, technical aspects of ultrasound administration and the possible potentiating effect of microbubbles.

Objectives: To assess the effectiveness and safety of sonothrombolysis in patients with acute ischaemic stroke.

Sonothrombolysis for acute ischaemic stroke.

Background: Sonothrombolysis is a promising but unproven tool for treating acute ischaemic stroke. There is an ongoing debate about the efficacy, safety, technical aspects of ultrasound administration and the possible potentiating effect of microbubbles.

Objectives: To assess the effectiveness and safety of sonothrombolysis in patients with acute ischaemic stroke.