The normal uncinate process: histology and clinical relevance.

In this three-center, prospective, non-randomized, controlled trial, we performed a qualitative and quantitative histological and morphometric assessment of the normal uncinate process (UP). The soft tissue and bony elements of the normal UP of 16 adults were investigated and compared with 28 age- and gender-matched archival reference-group samples of neighboring structures of the inferior and middle turbinates. A series of measurements were taken and included the thickness of the mucosal layers and bone, epithelial height, basement membrane thickness, number of lamina propria inflammatory cells, and the area fraction (AF) of the epithelium, connective tissue, glands, veins and arteries.

Pediatric chronic rhinosinusitis histopathology: differences and similarities with the adult form.

Objective: To compare the histopathology and immunohistochemistry of pediatric and adult chronic rhinosinusitis (CRS).

Study Design: Cross-sectional study.

Setting: University-affiliated hospital.

Glycoconjugate expression of sinus mucosa in chronic rhinosinusitis: a lectin histochemical study.

Background: Glycoproteins are responsible for the rheological properties of the mucus. Changes in mucus viscosity may interfere with mucociliary clearance, leading to stasis and aggravation of chronic rhinosinusitis (CRS). The purpose of this study was to assess the composition and concentration of various sinus mucosa glycoproteins in normal and chronically inflamed sinuses.

Glycoconjugate expression in perennial allergic rhinitis: a lectin histopathological study.

Conclusions: The data show that differences in the concentrations of glycoconjugates of patients with perennial allergic rhinitis (PAR) and normal controls are modest, thus indicating that the composition of the mucus in allergic patients largely resembles that of healthy individuals. The findings may point to the need for volume reduction methods controlling mucus production in patients with PAR.

Objectives: We aimed to study the composition and concentration of inferior turbinate glycoconjugates of patients with PAR.

Glycoconjugate expression in normal human inferior turbinate mucosa: a lectin histochemical study.

Background: Further study on the composition and concentration of normal nasal mucosal glycoconjugates is needed.

Methods: A battery of ten lectins was used to stain six carbohydrates residing in the inferior turbinate mucosa of 21 healthy individuals.

Results: The concentrations of glycoconjugates of the glycocalyx exceeded that of epithelial goblet, ciliated, and basal cells, and also of mucous, serous, and mixed submucosal glands.