[Molecular diagnostic tests for thrombophilia in patients referred to genetic counseling clinic because due to recurrent pregnancy failure. One center's experience].

Unlabelled: The loss of three or more subsequent pregnancies before the end of the 22nd week is observed in 0.4-1% of women. Despite great advances in medicine, the causes of pregnancy failure (miscarriages, missed abortions and stillbirths), and the birth of a child or children with congenital abnormalities, are still not determined precisely

The Aim: The purpose of the research was to determine the association of polymorphisms and mutations of coagulation factors II and V genes, as well as methylenetethrahydrofolate reductase (MTHFR) gene polymorphism, with the course of pregnancy and the type of reproductive failure.

A brain dead woman, giving birth in the 23rd week of pregnancy, used as an organ donor: a case report.

Background: Maternal brain death during pregnancy is an exceptional case when somatic support might be continued despite diagnosed death. There are only a few cases of maternal brain death during pregnancy reported in the literature and detailed data regarding the frequency of such cases are lacking.

Case Report: The case of a 40-year-old woman, diagnosed brain dead due to a subarachnoid and intracranial hemorrhage in the 21st week of pregnancy is presented.

[Antithrombin and protein C activity in the blood of premature newborns with intrauterine growth retardation].

Unlabelled: Intrauterine growth retardation (IUGR) and prematurity are often correlated with higher mortality and morbidity in the first days of life especially due to complications such as: hypoglycemia, polycythemia, necrotizing enterocolitis, meconium aspiration syndrome. Disturbances in the haemostatic system could be responsible for poor outcome of these complications.

Aim: To determine the activity of main inhibitor of coagulation-antithrombin, level of protein C, concentration of thrombin-antithrombin (TAT) complexes and fibrinogen in the blood of premature infants with intrauterine growth retardation (IUGR) in comparison with premature infants without IUGR.

[IgE-dependent allergy--the intensification factor of gastroesophageal reflux in children and youth].

Unlabelled: THE AIM of the study was an attempt to determine the correlation between the incidence of IgE - dependent allergy and the severity of gastro-oesophageal reflux in children and youth.

Patients And Methods: 222 patients aged from 1 to 16 years with diagnosed acidic gastro-oesophageal reflux on the basis of all day ph observations were enrolled to the study. IgE - dependent allergy was diagnosed on the basis of the history, physical examination, evaluation of cIgE concentration in serum and the results of skin tests with chosen food and pollen allergens.

[A case of vascular malformation in vertebral artery region in a 12-year-old boy].

The authors present a case of cerebral vascular malformation in vertebral artery region which was found in 12-years old boy with hemiparesis.