Publications by authors named "Tatiana Georgiesh"

Article Synopsis
  • Researchers created a new risk model called G-score to better predict if patients with solitary fibrous tumors will have recurrences, or if their disease will come back.
  • They studied a large group of 318 patients worldwide and found that 33% had their disease come back over time.
  • The G-score did a really good job at predicting who was at low risk for recurrence compared to other models, which means patients with a low score might not need to visit the doctor as often.
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Solitary fibrous tumour (SFT) is a mesenchymal neoplasm characterised by pathognomonic NAB2-STAT6 gene fusions. The clinical implications and prognostic value of different fusion variants has not been clarified. In the current study, we explore the clinicopathological, prognostic and molecular differences between tumours with different fusions.

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Aims: Solitary fibrous tumours (SFTs) are rare mesenchymal neoplasms with recurrence rates of 10-30%. Current risk stratification systems for extrameningeal SFTs are based on cohorts with limited follow-up and are not suitable for prediction of late recurrences. In this study we aimed to develop a prognostic model accounting for both early and late recurrences using a relatively large patient cohort with long-term follow-up.

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