Publications by authors named "Tatiana Deniskova"

Article Synopsis
  • The study analyzed the genetic makeup of Orenburg goats using SNP data from modern and historical samples, revealing that the genetic characteristics from older populations have persisted in current goats.
  • Findings indicated low inbreeding rates and maintained genetic diversity, providing a basis for selective breeding and potential conservation strategies through gamete preservation.
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  • The growing demand for eco-friendly and diverse pig feeding systems highlights the importance of rearing and conserving local pig breeds, like the Livni pig, which is well-adapted to Russia's environment.
  • A study analyzed the genetic diversity of Livni pigs using SNP data from different populations and compared it to commercial breeds like Landrace and Large White.
  • Results showed that Livni pigs have higher genetic diversity, lower inbreeding, and a unique population structure, indicating less selection pressure compared to mainstream commercial breeds.
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Goats with diverse economic phenotypic traits play an important role in animal husbandry. However, the genetic mechanisms underlying complex phenotypic traits are unclear in goats. Genomic studies of variations provided a lens to identify functional genes.

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Eurasia is represented by all climatic zones and various environments. A unique breed variety of farm animals has been developed in Russia, whose territory covers a large area of the continent. A total of 69 local breeds and types of dairy, wool, and meat sheep () are maintained here.

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  • The study focused on understanding the global historical and genetic relationships between Merino sheep and their derived breeds by genotyping 19 populations and analyzing additional data from 23 populations.
  • Several statistical tests confirmed that the genetic diversity in Merino breeds is influenced by their geographic origin and local admixture, particularly highlighting the impact of Australian, Rambouillet, and German strains.
  • The research identified 106 candidate genes under potential selection, including those related to immune response, growth, morphology, and reproductive traits, indicating the genetic adaptations of Merino sheep to different climates.
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In goat breeds, the domestication followed by artificial selection for economically important traits have shaped genetic variation within populations, leading to the fixation of specific alleles for specific traits. This led to the formation and evolution of many different breeds specialised and raised for a particular purpose. However, and despite the intensity of artificial selection, natural selection continues acting, possibly leaving a more diluted contribution over time, whose traces may be more difficult to capture.

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The objective of this study was to identify the SNPs and candidate genes related to body weight and seven body conformation traits at the age of 8 months in the Russian aboriginal Karachai goats (n = 269) by conducting genome-wide association studies (GWAS), using genotypes generated by Goat SNP BeadChip (Illumina Inc., USA). We identified 241 SNPs, which were significantly associated with the studied traits, including 47 genome-wide SNPs (p < 10−5) and 194 suggestive SNPs (p < 10−4), distributed among all goat autosomes except for autosome 23.

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Poaching is one of the major types of wildlife crime in Russia. Remnants of goats (presumably the wild endemic species, the Caucasian tur) were found in an area of the Caucasian mountains. The case study involves a suspected poacher whose vehicle was found to have two duffel bags containing pieces of a carcass, which he claimed was that of a goat from his flock.

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Specific local environmental and sociocultural conditions have led to the creation of various goat populations in Russia. National goat diversity includes breeds that have been selected for down and mohair production traits as well as versatile local breeds for which pastoralism is the main management system. Effective preservation and breeding programs for local goat breeds are missing due to the lack of DNA-based data.

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  • Gotland sheep, native to Gotland, Sweden, split from the Gute sheep breed about 100 years ago and has gained popularity for its high-quality pelts.
  • A study analyzed 600 K SNP genotype data to estimate shared ancestors and identify genetic selection signatures, finding the Gotland breed is distinct yet shares ancestry with several other breeds.
  • Significant SNPs linked to candidate genes impacting wool quality, fertility, and growth traits were identified, offering insights into the genetics underlying important economic traits in sheep.
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  • The Karachaev goat is a local breed native to the North-Caucasus region of Russia.
  • The complete mitochondrial genome of this breed was analyzed, measuring 16,624 base pairs (bp) in length.
  • The analysis revealed that this specific specimen belongs to haplogroup A.
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  • This study examined the genetic characteristics and selection signatures of two Russian native cattle breeds, Yaroslavl and Kholmogor, using high-density SNP genotyping and a variety of statistical analyses.
  • Researchers identified nine selection regions in Yaroslavl and six in Kholmogor, with some overlap with Holstein cattle but also discovered three unique selection sweeps in each breed.
  • The findings also included a list of candidate genes linked to these genomic regions, and the potential role of these genes in artificial selection related to the breeds' genetic evolution.
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How animals, particularly livestock, adapt to various climates and environments over short evolutionary time is of fundamental biological interest. Further, understanding the genetic mechanisms of adaptation in indigenous livestock populations is important for designing appropriate breeding programs to cope with the impacts of changing climate. Here, we conducted a comprehensive genomic analysis of diversity, interspecies introgression, and climate-mediated selective signatures in a global sample of sheep and their wild relatives.

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  • * Researchers found high genetic diversity among the Russian goat breeds and identified 59 distinct haplotypes, with most clustered in haplogroup A, aligning with global goat lineage patterns.
  • * The findings suggest that local goats were introduced to Russia through multiple migration routes, with potential implications for the recognition and conservation of these breeds.
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Background: Domestication and centuries of selective breeding have changed genomes of sheep breeds to respond to environmental challenges and human needs. The genomes of local breeds, therefore, are valuable sources of genomic variants to be used to understand mechanisms of response to adaptation and artificial selection. As a step toward this we performed a high-density genotyping and comprehensive scans for signatures of selection in the genomes from 15 local sheep breeds reared across Russia.

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Sheep are a main livestock species of Kyrgyzstan, a Central Asian country with predominating mountain terrain. The current gene pool of local sheep resources has been forming under diverse climate conditions from the era of the trading caravans of the Great Silk Road, through the Soviet period of large-scale livestock improvements, which was followed by the deep crisis at the end of the 20th century, up to now. However, not much is known about the genetic background and variability of the local sheep populations.

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Reindeer (Rangifer tarandus L. 1758) are an essential element of the Russian Far North, providing a significant source of nutrition for the representatives of 18 ethnicities. The species has wild and domestic forms, which are in constant interaction.

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Insights into the genetic characteristics of a species provide important information for wildlife conservation programs. Here, we used the OvineSNP50 BeadChip developed for domestic sheep to examine population structure and evaluate genetic diversity of snow sheep () inhabiting Verkhoyansk Range and Momsky Ridge. A total of 1,121 polymorphic SNPs were used to test 80 specimens representing five populations, including four populations of the Verkhoyansk Mountain chain: Kharaulakh Ridge-Tiksi Bay (TIK, =22), Orulgan Ridge (ORU, =22), the central part of Verkhoyansk Range (VER, =15), Suntar-Khayata Ridge (SKH, =13), and Momsky Ridge (MOM, =8).

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  • The study investigates the population structure and origins of nine Russian cattle breeds, linking them to various historical and cultural influences in Russia.
  • Genotyping using SNP analysis shows similar genetic diversity in eight breeds, with Yakut being notably different and identified as having unique Turano-Mongolian ancestry.
  • The research concludes that some Russian breeds maintain a more authentic genetic profile with less introgression from foreign breeds, while others display transboundary European ancestry from well-known breeds like Holstein and Brown Swiss.
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Background: Russia has a diverse variety of native and locally developed sheep breeds with coarse, fine, and semi-fine wool, which inhabit different climate zones and landscapes that range from hot deserts to harsh northern areas. To date, no genome-wide information has been used to investigate the history and genetic characteristics of the extant local Russian sheep populations. To infer the population structure and genome-wide diversity of Russian sheep, 25 local breeds were genotyped with the OvineSNP50 BeadChip.

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