Variation of antibody responses to antigen with parasitaemia and polymorphism in Khartoum state, Sudan.

A hospital-based cross-sectional study was conducted at Khartoum state to investigate the variation of antibody responses to 19-kDa C-terminal region of merozoite surface protein 1 antigen and the variation of human polymorphism with parasitaemia. Measurements of natural acquisition of anti- IgG, IgG1 and IgG3 antibodies were performed using ELISA. Molecular characterization of polymorphism was achieved.