Publications by authors named "Tasneem F. Mohammad"

Numerous anthropogenic ultraviolet filters (UVF) have been detected in aquatic environments and concerns have arisen regarding their potential impacts on aquatic organisms. This manuscript reviews the environmental concentrations and potential toxicity of various UVF. The highest concentrations of UVF are typically observed near frequently visited recreational areas and during peak water-activity periods, which suggests that sunscreen application correlates with noticeable alterations in UVF concentrations.

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  • OTC oral supplements are popular for treating skin conditions but lack standard regulations, which may create risks for users and healthcare providers.
  • The review highlights the issues of adulterated products and the nuances of authenticity labels (like USP and NSF) that can confuse consumers and clinicians.
  • It provides guidance on how to effectively assess these supplements and understand the authenticity labels to support better decision-making in dermatology.
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  • Patients with hyperpigmentation face significant psychosocial challenges, highlighting the need for effective treatments.
  • Hydroquinone is the current standard treatment, but concerns over its side effects have led to the development of alternative therapies.
  • Various agents, including cysteamine and glutathione, can shift melanin production from eumelanin to pheomelanin, and it’s important to educate patients about photoprotection to mitigate risks associated with increased pheomelanin.
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  • - Disorders of hyperpigmentation are common and hydroquinone is a widely used treatment, despite potential side effects like acne, skin discoloration (ochronosis), and irritation.
  • - Rarely, hydroquinone can cause leukoderma, typically limited to the area where it is applied, but a unique case is reported involving widespread facial leukoderma from localized use.
  • - The reported leukoderma can be effectively treated using methods for vitiligo, if addressed promptly and correctly.
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  • * A comprehensive physical examination and medication history are crucial for identifying the specific offending drug, as DIP typically results from melanin accumulation or drug and iron deposition in the skin.
  • * Preventive measures like using broad-spectrum sunscreen and photoprotective clothing are important, and various laser treatments have shown effectiveness in clearing DIP.
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  • Tinted sunscreens offer UV and visible light protection and are designed to match all skin tones, unlike traditional sunscreens.
  • A study evaluated 7 different tinted sunscreens for color match and user satisfaction across various skin types (Fitzpatrick phototypes I-VI) by applying them on subjects' arms and using photography and surveys.
  • Results showed that while many products matched well for medium skin tones (SPT III-IV), very light (SPT I-II) and very dark skin tones (SPT V-VI) had limited options with only a few suitable matches found.
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  • A study aimed to evaluate how consistent and accurate trained raters are when using two versions of the Vitiligo Area Scoring Index (T-VASI and F-VASI) to assess the severity of vitiligo in participants.
  • Results showed that inter-rater reliability improved for facial assessments, while overall reliability for full-body assessments was consistently good, indicating the method is effective.
  • Limitations included a small sample size and the lack of in-person evaluations, but the findings suggest the Vitiligo Area Scoring Index is a reliable tool for assessing vitiligo severity when used by trained individuals.
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  • Hydroquinone has been traditionally used to treat skin conditions like melasma, hyperpigmentation, and photoaging due to its effectiveness as a lightening agent.
  • Recent concerns about its safety have led to a ban on over-the-counter products containing hydroquinone in the U.S.
  • This paper presents an updated review of studies on the safety of hydroquinone from the last 15 years, considering new findings since earlier reviews.
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Background: The human skin microbiome is a dynamic ecosystem that plays an important role in skin health. The skin microbiome has been implicated in numerous diseases, and our knowledge surrounding it continues to evolve. A better understanding of the interactions between the environment and the skin microbiome will lead to improvements in skin health.

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Vitiligo manifests as depigmented macules and patches on the skin and can significantly impact a patient's quality of life. Despite the availability of several treatment modalities, rates of repigmentation can vary widely among individuals and disease subtypes. For patients with stable vitiligo who have not achieved satisfactory results with medical treatments, the melanocyte-keratinocyte transplantation procedure (MKTP) is a viable option.

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Little is known about hair loss associated with wearing the hijab, a religious head covering worn by Muslim women. We performed a single-center analysis to investigate the association between various forms of non-scarring alopecia and wearing the hijab. This study included 125 patients who wore the hijab and 40 race/ethnicity-matched women who did not wear the hijab.

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Understanding individuals' skin pigmentation and photosensitivity is important in judging risk of skin cancer and response to certain treatment modalities. However, individuals with darkly pigmented skin are poorly represented in the widely used Fitzpatrick skin phototype (FST) system. Moreover, the FST system is prone to misuse, as it relies on subjective patient and clinician assessment of skin type, and does not clearly differentiate pigmentation from photosensitivity.

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Sunscreens are an important means of protection against sunburns, dyspigmentation, photoaging, and photocarcinogenesis. Sunscreens come in a variety of formulations that can protect against ultraviolet B (UVB) radiation, both UVB and ultraviolet A (UVA) radiation (broad-spectrum sunscreens), and UVB, UVA, and visible light (tinted broad-spectrum sunscreens). In the USA, there is currently a paucity of FDA-approved broad-spectrum filters on the market.

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  • The autologous noncultured melanocyte keratinocyte transplant procedure (MKTP) is an effective method for repigmentation in patients with vitiligo, but the best recipient-to-donor (RD) ratio for optimal results is still unknown.
  • A study involving 120 patients found that those with focal/segmental vitiligo (SV) showed higher repigmentation rates (80.2% mean improvement) compared to those with non-segmental vitiligo (58.3%) and leukoderma/piebaldism (51.8%), with a notable finding that non-white patients had a higher RD ratio.
  • The results indicate that while lower RD ratios were associated with better outcomes, the type
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Hyperpigmentation is a common and distressing dermatologic condition. Since tyrosinase (TYR) plays an essential role in melanogenesis, its inhibition is considered a logical approach along with other therapeutic methods to prevent the accumulation of melanin in the skin. Thus, TYR inhibitors are a tempting target as the medicinal and cosmetic active agents of hyperpigmentation disorder.

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